Start-up Latin America 2016 presents an overview of policies to support start-ups in Chile, Colombia, Mexico and Peru. This overview presents the main results and recommendations from the study. Even though there is an unfavourable macroeconomic climate and there are still innovation gaps between Latin America and more advanced countries, start-ups are revealing a different, more dynamic side to the region. Since 2010, the concept of start-ups has attracted growing attention from the media, investors and policy makers in Latin America, and countries have implemented various programmes to support start-ups. These policies to promote startups have evolved rapidly, and in the space of just six years, their design, focus and structure have changed significantly, showing initial results and revealing a change in people’s perceptions of the region as a place for entrepreneurship and innovation.