Mark | Date Date | Title Title | |||
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04 Jul 2023 |
Test No. 126: Determination of the Hydrophobicity Index of Nanomaterials Through an Affinity Measurement
This Test Guideline (TG) describes a method to determine the hydrophobicity index (Hy) of nanomaterials (NMs), through an affinity measurement. Hydrophobicity is defined as "the association of non-polar groups or molecules in an aqueous environment... |
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04 Jul 2023 |
Test No. 125: Nanomaterial Particle Size and Size Distribution of Nanomaterials
This Test Guideline, covering nanomaterials spanning from 1 nm to 1000 nm, is intended for particle size and particle size distribution measurements of nanomaterials. |
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30 Jun 2022 |
Test No. 124: Determination of the Volume Specific Surface Area of Manufactured Nanomaterials
This Test Guideline (TG) describes a harmonised procedure to determine the Volume Specific Surface Area (VSSA) of powdered solid manufactured nanomaterials (MNs). |
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30 Jun 2022 |
Test No. 123: Partition Coefficient (1-Octanol/Water): Slow-Stirring Method
This Test Guideline describes the slow-stirring method, which permits the determination of the 1-octanol/water partition coefficient (POW) values up to a log POW of 8.2. The partition coefficient between water and 1-octanol (POW) is defined as the ... |
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26 Jul 2013 |
Test No. 122: Determination of pH, Acidity and Alkalinity
This Test Guideline describes the procedure for the electronic determination of pH of an undiluted aqueous solution or dispersion, the pH of a dilution of a solution or dispersion in water, or the pH of a chemical diluted to end-use concentration ... |
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22 Jan 2001 |
Test No. 121: Estimation of the Adsorption Coefficient (Koc ) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC)
This Test Guideline describes an experimental method using HPLC for the estimation of the adsorption coefficient Koc in soil and in sewage sludge. The adsorption coefficient is defined as the ratio between the concentration of the substance in the ... |
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21 Jan 2000 |
Test No. 120: Solution/Extraction Behaviour of Polymers in Water
This Test Guideline describes a method to analyse the solution/extraction behaviour of polymers in water, which uses the flask method with modifications. Three samples of 10 g of particles of the test substance are weighed into each of three vessels ... |
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14 Jun 1996 |
Test No. 119: Determination of the Low Molecular Weight Content of a Polymer Using Gel Permeation Chromatography
This Test guideline describes the Gel Permeation Chromatography (GPC). This method permits to determine the molecular weight distribution and the average molecular weights (Mn, Mw). GPC is a special type of liquid chromatography in which the sample ... |
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14 Jun 1996 |
Test No. 118: Determination of the Number-Average Molecular Weight and the Molecular Weight Distribution of Polymers using Gel Permeation Chromatography
This Test guideline describes the Gel Permeation Chromatography (GPC). This method permits to determine the molecular weight distribution and the average molecular weights (Mn, Mw). GPC is a special type of liquid chromatography in which the sample ... |
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30 Jun 2022 |
Test No. 117: Partition Coefficient (n-octanol/water), HPLC Method
This Test Guideline describes the HPLC method, which permits to determine the partition coefficient (n-octanol/water) (Pow). Reverse phase HPLC is performed on analytical columns packed with a solid phase containing long hydrocarbon chains ... |
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12 May 1981 |
Test No. 116: Fat Solubility of Solid and Liquid Substances
This Test Guideline describes a method to determine the fat solubility of solid and liquid substances. The fat solubility of a substance is one of the data for evaluating the storage of lipid soluble materials in biological tissue. This test method ... |
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27 Jul 1995 |
Test No. 115: Surface Tension of Aqueous Solutions
This Test Guideline describes methods to determine the surface tension (in N/m) of aqueous solutions. The methods are based on the measurement of the force which it is necessary to exert vertically on a stirrup or ring, in contact with the surface ... |
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02 Oct 2012 |
Test No. 114: Viscosity of Liquids
This Test Guideline describes methods to measure the viscosity of liquids. Most of the methods listed are appropriate for the investigation of Newtonian liquids. The measurement of non-Newtonian liquids is possible with the rotational viscometer ... |
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12 May 1981 |
Test No. 113: Screening Test for Thermal Stability and Stability in Air
This Test Guideline describes methods for determining storage stability of a substance with respect to heat and air. Two methods are applicable to homogeneous solid and liquid substances and to mixtures of these: the accelerated storage test and the ... |
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12 May 1981 |
Test No. 112: Dissociation Constants in Water
This Test Guideline describes the methods allowing the determination of the dissociation constants in water. The dissociation is the reversible splitting into two or more chemical species which may be ionic. The determination of the dissociation ... |
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23 Nov 2004 |
Test No. 111: Hydrolysis as a Function of pH
This Test Guideline describes a laboratory test method to assess abiotic hydrolytic transformations of chemicals in aquatic systems at pH values normally found in the environment (pH 4 – 9). This Guideline is designed as a tiered approach; each tier ... |
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12 May 1981 |
Test No. 110: Particle Size Distribution/ Fibre Length and Diameter Distributions
This Test Guideline describes two methods. These tests are applicable only to water insoluble (solubility < 10-6 g/1) substances. The first method described (Method A) is designed to provide information on the transportation and sedimentation of ... |
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02 Oct 2012 |
Test No. 109: Density of Liquids and Solids
This Test Guideline lists methods for determining the density of liquids and solids, giving only a succinct description of them. The density of a substance is the quotient of its mass and its volume and is expressed in SI units as kg/m3 at a ... |
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12 May 1981 |
Test No. 108: Complex Formation Ability in Water
This Test Guideline describes the polarographic method. The ability of a substance to form complexes with metals can be assessed by means of polarographic techniques which allow the determination of stability constants for some complexes. The ... |
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27 Jul 1995 |
Test No. 107: Partition Coefficient (n-octanol/water): Shake Flask Method
This Test Guideline describes a method to determine experimentally Pow values in the range log Pow between -2 and 4 (occasionally up to 5). This method can not be used with surface-active materials. The partition coefficient is defined as the ratio ... |
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- Books
- OECD Guidelines for the Testing of Chemicals
- OECD Guidelines for the Testing of Chemicals, Section 1
OECD Guidelines for the Testing of Chemicals, Section 1
Physical-Chemical properties
The OECD Guidelines for the Testing of Chemicals is a collection of about 150 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of chemicals. They are a set of tools for professionals, used primarily in regulatory safety testing and subsequent chemical and chemical product notification, chemical registration and in chemical evaluation. They can also be used for the selection and ranking of candidate chemicals during the development of new chemicals and products and in toxicology research. This group of tests covers physical-chemical properties.
English Also available in: French
- ISSN: 20745753 (online)
- https://doi.org/10.1787/20745753
1 - 20 of 27 results
Test No. 126: Determination of the Hydrophobicity Index of Nanomaterials Through an Affinity Measurement
OECD
04 Jul 2023
This Test Guideline (TG) describes a method to determine the hydrophobicity index (Hy) of nanomaterials (NMs), through an affinity measurement. Hydrophobicity is defined as "the association of non-polar groups or molecules in an aqueous environment...
This Test Guideline, covering nanomaterials spanning from 1 nm to 1000 nm, is intended for particle size and particle size distribution measurements of nanomaterials.
Test No. 124: Determination of the Volume Specific Surface Area of Manufactured Nanomaterials
OECD
30 Jun 2022
This Test Guideline (TG) describes a harmonised procedure to determine the Volume Specific Surface Area (VSSA) of powdered solid manufactured nanomaterials (MNs).
This Test Guideline describes the slow-stirring method, which permits the determination of the 1-octanol/water partition coefficient (POW) values up to a log POW of 8.2. The partition coefficient between water and 1-octanol (POW) is defined as the ...
Test No. 122: Determination of pH, Acidity and Alkalinity
OECD
26 Jul 2013
This Test Guideline describes the procedure for the electronic determination of pH of an undiluted aqueous solution or dispersion, the pH of a dilution of a solution or dispersion in water, or the pH of a chemical diluted to end-use concentration ...
Test No. 121: Estimation of the Adsorption Coefficient (Koc ) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC)
OECD
22 Jan 2001
This Test Guideline describes an experimental method using HPLC for the estimation of the adsorption coefficient Koc in soil and in sewage sludge. The adsorption coefficient is defined as the ratio between the concentration of the substance in the ...
Test No. 120: Solution/Extraction Behaviour of Polymers in Water
OECD
21 Jan 2000
This Test Guideline describes a method to analyse the solution/extraction behaviour of polymers in water, which uses the flask method with modifications. Three samples of 10 g of particles of the test substance are weighed into each of three vessels ...
Test No. 119: Determination of the Low Molecular Weight Content of a Polymer Using Gel Permeation Chromatography
OECD
14 Jun 1996
This Test guideline describes the Gel Permeation Chromatography (GPC). This method permits to determine the molecular weight distribution and the average molecular weights (Mn, Mw). GPC is a special type of liquid chromatography in which the sample ...
Test No. 118: Determination of the Number-Average Molecular Weight and the Molecular Weight Distribution of Polymers using Gel Permeation Chromatography
OECD
14 Jun 1996
This Test guideline describes the Gel Permeation Chromatography (GPC). This method permits to determine the molecular weight distribution and the average molecular weights (Mn, Mw). GPC is a special type of liquid chromatography in which the sample ...
Test No. 117: Partition Coefficient (n-octanol/water), HPLC Method
OECD
30 Jun 2022
This Test Guideline describes the HPLC method, which permits to determine the partition coefficient (n-octanol/water) (Pow). Reverse phase HPLC is performed on analytical columns packed with a solid phase containing long hydrocarbon chains ...
Test No. 116: Fat Solubility of Solid and Liquid Substances
OECD
12 May 1981
This Test Guideline describes a method to determine the fat solubility of solid and liquid substances. The fat solubility of a substance is one of the data for evaluating the storage of lipid soluble materials in biological tissue. This test method ...
Test No. 115: Surface Tension of Aqueous Solutions
OECD
27 Jul 1995
This Test Guideline describes methods to determine the surface tension (in N/m) of aqueous solutions. The methods are based on the measurement of the force which it is necessary to exert vertically on a stirrup or ring, in contact with the surface ...
Test No. 114: Viscosity of Liquids
OECD
02 Oct 2012
This Test Guideline describes methods to measure the viscosity of liquids. Most of the methods listed are appropriate for the investigation of Newtonian liquids. The measurement of non-Newtonian liquids is possible with the rotational viscometer ...
This Test Guideline describes methods for determining storage stability of a substance with respect to heat and air. Two methods are applicable to homogeneous solid and liquid substances and to mixtures of these: the accelerated storage test and the ...
Test No. 112: Dissociation Constants in Water
OECD
12 May 1981
This Test Guideline describes the methods allowing the determination of the dissociation constants in water. The dissociation is the reversible splitting into two or more chemical species which may be ionic. The determination of the dissociation ...
Test No. 111: Hydrolysis as a Function of pH
OECD
23 Nov 2004
This Test Guideline describes a laboratory test method to assess abiotic hydrolytic transformations of chemicals in aquatic systems at pH values normally found in the environment (pH 4 – 9). This Guideline is designed as a tiered approach; each tier ...
This Test Guideline describes two methods. These tests are applicable only to water insoluble (solubility < 10-6 g/1) substances. The first method described (Method A) is designed to provide information on the transportation and sedimentation of ...
Test No. 109: Density of Liquids and Solids
OECD
02 Oct 2012
This Test Guideline lists methods for determining the density of liquids and solids, giving only a succinct description of them. The density of a substance is the quotient of its mass and its volume and is expressed in SI units as kg/m3 at a ...
Test No. 108: Complex Formation Ability in Water
OECD
12 May 1981
This Test Guideline describes the polarographic method. The ability of a substance to form complexes with metals can be assessed by means of polarographic techniques which allow the determination of stability constants for some complexes. The ...
This Test Guideline describes a method to determine experimentally Pow values in the range log Pow between -2 and 4 (occasionally up to 5). This method can not be used with surface-active materials. The partition coefficient is defined as the ratio ...