This report addresses the commercial availability and current uses of alternatives (chemical and non-chemical) to per- and polyfluoroalkyl substances (PFASs) in food packaging (paper and paperboard). PFASs are synthetic substances that are widely used in numerous technologies, industrial processes and everyday applications. Since the discovery of polytetrafluoroethylene (PTFE) in 1938, PFASs, both polymeric and non-polymeric, have been used extensively in various industries worldwide, due to their dielectrical properties, resistance to heat and chemical agents, low surface energy and low friction properties, etc. Due to the large variety of PFAS substances captured in the OECD definition, the individual PFAS will have different properties, however, in general, the highly stable carbon-fluorine bond and the unique physicochemical properties of PFASs make these substances valuable ingredients for products with high versatility, strength, resilience and durability. Based upon this review, a number of policy recommendations are suggested in this report as well as areas that may be considered for further work. These have been divided into those aimed at international organisations and those aimed at industry.