Sélectionner | Date Date | Titre Titre | |||
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25 Jun 2024 |
Test No. 252: Rapid Estrogen Activity In Vivo (REACTIV) assay
This Test Guideline describes a Rapid Estrogen ACTivity In Vivo (REACTIV) Assay in an aquatic assay that utilises transgenic Oryzias latipes (Japanese medaka) eleutheroembryos at day post hatch zero, in a multi-well plate format to identify chemicals... |
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25 Jun 2024 |
Test No. 253: Short-term juvenile hormone (JH) activity screening assay in Daphnia magna
This Test Guideline (TG) describes a short-term juvenile hormone (JH) activity screening assay using Daphnia magna to detect the potential of chemicals with JH activity. The JHASA was designed as a screen assay which evaluates male offspring... |
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04 Jul 2023 |
Test No. 240: Medaka Extended One Generation Reproduction Test (MEOGRT)
This Test Guideline describes the Medaka Extended One Generation Test (MEOGRT), which exposes fish over multiple generations to give data relevant to ecological hazard and risk assessment of chemicals, including suspected endocrine disrupting... |
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04 Jul 2023 |
Test No. 219: Sediment-Water Chironomid Toxicity Using Spiked Water
This Test Guideline is designed to assess the effects of prolonged exposure of chemicals to the sediment-dwelling larvae of the freshwater dipteran Chironomus sp. First instar chironomid larvae are exposed to at least five concentrations of the test ... |
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04 Jul 2023 |
Test No. 218: Sediment-Water Chironomid Toxicity Using Spiked Sediment
This Test Guideline is designed to assess the effects of prolonged exposure of chemicals to the sediment-dwelling larvae of the freshwater dipteran Chironomus sp. First instar chironomid larvae are exposed to at least five concentrations of the test ... |
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30 Jun 2022 |
Test No. 251: Rapid Androgen Disruption Activity Reporter (RADAR) assay
The Rapid Androgen Disruption Activity Reporter (RADAR) Test Guideline describes an aquatic assay that utilizes transgenic Oryzias latipes (O. latipes, Japanese medaka) eleutheroembryos at day post hatch zero, in a multi-well format to detect... |
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18 Jun 2021 |
Test No. 249: Fish Cell Line Acute Toxicity - The RTgill-W1 cell line assay
The RTgill-W1 cell line assay describes a 24-well plate format fish cell line acute toxicity test using the permanent cell line from rainbow trout (Oncorhynchus mykiss) gill, RTgill-W1. After 24 h of exposure to the test chemical, cell viability is... |
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17 Jun 2021 |
Test No. 250: EASZY assay - Detection of Endocrine Active Substances, acting through estrogen receptors, using transgenic tg(cyp19a1b:GFP) Zebrafish embrYos
The EASZY assay is a mechanism-based in vivo screening assay designed to detect endocrine active chemicals acting as agonist through estrogen receptors (ERs), by inducing the expression of the green fluorescent protein (GFP) driven by the cyp19a1b... |
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18 Jun 2019 |
Test No. 248: Xenopus Eleutheroembryonic Thyroid Assay (XETA)
The purpose of the test is to measure the capacity of a chemical to activate or inhibit the transcription of a genetic construct (THb/ZIP-GFP X. laevis eleutheroembryos) either by binding to the thyroid hormone receptor or by modifying the amount of... |
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18 Jun 2019 |
Test No. 203: Fish, Acute Toxicity Test
The fish are exposed to the test substance preferably for a period of 96 hours. Mortalities are recorded at 24, 48, 72 and 96 hours and the concentrations which kill 50 per cent of the fish (LC50) are determined where possible. One or more species ... |
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09 Oct 2017 |
Test No. 247: Bumblebee, Acute Oral Toxicity Test
This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The... |
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09 Oct 2017 |
Test No. 246: Bumblebee, Acute Contact Toxicity Test
This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The... |
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09 Oct 2017 |
Test No. 245: Honey Bee (Apis Mellifera L.), Chronic Oral Toxicity Test (10-Day Feeding)
This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The... |
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09 Oct 2017 |
Test No. 244: Protozoan Activated Sludge Inhibition Test
This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The... |
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29 Jul 2016 |
Test No. 232: Collembolan Reproduction Test in Soil
This Test Guideline is designed for assessing the effects of chemicals on the reproduction of collembolans in soil. |
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29 Jul 2016 |
Test No. 228: Determination of Developmental Toxicity to Dipteran Dung Flies(Scathophaga stercoraria L. (Scathophagidae), Musca autumnalis De Geer (Muscidae))
This Test Guideline describes a method to estimate the developmental toxicity of a test chemical to the dung dwelling life stages of dung-dependent dipteran species. |
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29 Jul 2016 |
Test No. 226: Predatory mite (Hypoaspis (Geolaelaps) aculeifer) reproduction test in soil
This Test Guideline describes a method to assess the effects of chemical substances in soil on the reproductive output of the soil mite species Hypoaspis (Geolaelaps) aculeifer Canestrini (Acari: Laelapidae). It can be used for water soluble or... |
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29 Jul 2016 |
Test No. 223: Avian Acute Oral Toxicity Test
This Test Guideline describes procedures designed to estimate the acute oral toxicity of substances to birds, and it provides three testing options: (1) limit dose test, (2) LD50-slope test, and (3) LD50-only test. The LD50-slope and LD50-only... |
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29 Jul 2016 |
Test No. 222: Earthworm Reproduction Test (Eisenia fetida/Eisenia andrei)
This Test Guideline is designed to be used for assessing the effects of chemicals in soil on the reproductive output (and other sub-lethal end points) of the earthworm species Eisenia fetida or Eisenia andrei. |
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29 Jul 2016 |
Test No. 220: Enchytraeid Reproduction Test
This Test Guideline is designed to be used for assessing the effects of chemicals on the reproductive output of the enchytraeid worm, Enchytraeus albidus Henle 1873, in soil. |
- Accueil
- Livres
- OECD Guidelines for the Testing of Chemicals
- OECD Guidelines for the Testing of Chemicals, Section 2
OECD Guidelines for the Testing of Chemicals, Section 2
Effects on Biotic Systems
The OECD Guidelines for the Testing of Chemicals is a collection of about 150 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of chemicals. They are a set of tools for professionals, used primarily in regulatory safety testing and subsequent chemical and chemical product notification, chemical registration and in chemical evaluation. They can also be used for the selection and ranking of candidate chemicals during the development of new chemicals and products and in toxicology research. This group of tests covers effects on biotic systems.
Anglais Egalement disponible en : Français
- ISSN : 20745761 (en ligne)
- https://doi.org/10.1787/20745761
1 - 20 of 54 results
Test No. 252: Rapid Estrogen Activity In Vivo (REACTIV) assay
OCDE
25 Jun 2024
This Test Guideline describes a Rapid Estrogen ACTivity In Vivo (REACTIV) Assay in an aquatic assay that utilises transgenic Oryzias latipes (Japanese medaka) eleutheroembryos at day post hatch zero, in a multi-well plate format to identify chemicals...
Test No. 253: Short-term juvenile hormone (JH) activity screening assay in Daphnia magna
OCDE
25 Jun 2024
This Test Guideline (TG) describes a short-term juvenile hormone (JH) activity screening assay using Daphnia magna to detect the potential of chemicals with JH activity. The JHASA was designed as a screen assay which evaluates male offspring...
This Test Guideline describes the Medaka Extended One Generation Test (MEOGRT), which exposes fish over multiple generations to give data relevant to ecological hazard and risk assessment of chemicals, including suspected endocrine disrupting...
Test No. 219: Sediment-Water Chironomid Toxicity Using Spiked Water
OCDE
04 Jul 2023
This Test Guideline is designed to assess the effects of prolonged exposure of chemicals to the sediment-dwelling larvae of the freshwater dipteran Chironomus sp. First instar chironomid larvae are exposed to at least five concentrations of the test ...
This Test Guideline is designed to assess the effects of prolonged exposure of chemicals to the sediment-dwelling larvae of the freshwater dipteran Chironomus sp. First instar chironomid larvae are exposed to at least five concentrations of the test ...
The Rapid Androgen Disruption Activity Reporter (RADAR) Test Guideline describes an aquatic assay that utilizes transgenic Oryzias latipes (O. latipes, Japanese medaka) eleutheroembryos at day post hatch zero, in a multi-well format to detect...
The RTgill-W1 cell line assay describes a 24-well plate format fish cell line acute toxicity test using the permanent cell line from rainbow trout (Oncorhynchus mykiss) gill, RTgill-W1. After 24 h of exposure to the test chemical, cell viability is...
The EASZY assay is a mechanism-based in vivo screening assay designed to detect endocrine active chemicals acting as agonist through estrogen receptors (ERs), by inducing the expression of the green fluorescent protein (GFP) driven by the cyp19a1b...
Test No. 248: Xenopus Eleutheroembryonic Thyroid Assay (XETA)
OCDE
18 Jun 2019
The purpose of the test is to measure the capacity of a chemical to activate or inhibit the transcription of a genetic construct (THb/ZIP-GFP X. laevis eleutheroembryos) either by binding to the thyroid hormone receptor or by modifying the amount of...
Test No. 203: Fish, Acute Toxicity Test
OCDE
18 Jun 2019
The fish are exposed to the test substance preferably for a period of 96 hours. Mortalities are recorded at 24, 48, 72 and 96 hours and the concentrations which kill 50 per cent of the fish (LC50) are determined where possible. One or more species ...
Test No. 247: Bumblebee, Acute Oral Toxicity Test
OCDE
09 Oct 2017
This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The...
Test No. 246: Bumblebee, Acute Contact Toxicity Test
OCDE
09 Oct 2017
This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The...
Test No. 245: Honey Bee (Apis Mellifera L.), Chronic Oral Toxicity Test (10-Day Feeding)
OCDE
09 Oct 2017
This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The...
Test No. 244: Protozoan Activated Sludge Inhibition Test
OCDE
09 Oct 2017
This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The...
Test No. 232: Collembolan Reproduction Test in Soil
OCDE
29 Jul 2016
This Test Guideline is designed for assessing the effects of chemicals on the reproduction of collembolans in soil.
This Test Guideline describes a method to estimate the developmental toxicity of a test chemical to the dung dwelling life stages of dung-dependent dipteran species.
Test No. 226: Predatory mite (Hypoaspis (Geolaelaps) aculeifer) reproduction test in soil
OCDE
29 Jul 2016
This Test Guideline describes a method to assess the effects of chemical substances in soil on the reproductive output of the soil mite species Hypoaspis (Geolaelaps) aculeifer Canestrini (Acari: Laelapidae). It can be used for water soluble or...
Test No. 223: Avian Acute Oral Toxicity Test
OCDE
29 Jul 2016
This Test Guideline describes procedures designed to estimate the acute oral toxicity of substances to birds, and it provides three testing options: (1) limit dose test, (2) LD50-slope test, and (3) LD50-only test. The LD50-slope and LD50-only...
This Test Guideline is designed to be used for assessing the effects of chemicals in soil on the reproductive output (and other sub-lethal end points) of the earthworm species Eisenia fetida or Eisenia andrei.
Test No. 220: Enchytraeid Reproduction Test
OCDE
29 Jul 2016
This Test Guideline is designed to be used for assessing the effects of chemicals on the reproductive output of the enchytraeid worm, Enchytraeus albidus Henle 1873, in soil.