This chapter reviews Mexico City’s policies and practices designed to promote a culture of integrity in government, and it considers the challenges surrounding the National and Local Anti-corruption Systems. In line with the principles of the OECD Recommendation of the Council on Public Integrity, it provides recommendations for action in the normative framework and organisational culture, so to ensure its implementation. The chapter assesses the required changes for promoting ethics and managing conflicts of interest in Mexico City. Furthermore, it examines whether the newly adopted human resources policies and mechanisms are effective. Proposed actions intend to mainstream the integrity policies, legislation, regulations and practices in effect. They also intend to guarantee public servants’ compliance with regulations and raise awareness among all actors who interact with the various government entities. Finally, it examines the existing mechanism for ensuring citizen and stakeholder participation in monitoring integrity and accountability within the public administration.