This second edition of Health at a Glance: Latin America and the Caribbean, prepared jointly by OECD and the World Bank, presents a set of key indicators of health status, determinants of health, healthcare resources and utilisation, healthcare expenditure and financing, quality of care, health workforce, and ageing across 33 Latin America and the Caribbean countries. Each of the indicators is presented in a user-friendly format, consisting of charts illustrating variations across countries, and over time, brief descriptive analyses highlighting the major findings conveyed by the data, and a methodological box on the definition of the indicators and any limitations in data comparability. This edition of Health at a Glance: Latin America and the Caribbean also provides thematic analyses on two key topics for building more resilient health in the LAC region: the impact of the COVID-19 pandemic on LAC healthcare systems, and climate change and health.