This chapter presents an overview of policies to promote start-ups in Chile. Support for start-ups has shifted from a pilot phase to a more structured one in co-ordination with the national transformation strategy. Chile is strengthening the financing chain for start-ups, especially in early stages and is introducing new support services to entrepreneurs, including mentoring networks and collaborative workspaces. The country has also introduced conditionalities and incentives to encourage entrepreneurship in the regions within the country, to attract citizens who have studied abroad to return to Chile to do business, and to support social inclusion through entrepreneurship. It has taken steps to improve the legal framework for starting businesses, including a law to enable people to start a business in one day.