This chapter presents an overview of policies to support start-ups in Mexico. Between 2012 and 2016, Mexico has stepped up its support for start-ups. The country has bolstered institutions to promote start-ups and increased early-stage financing, thus addressing one of the main challenges identified in the first review of policies to promote start-ups (OECD, 2013a). It has also invested in promoting an entrepreneurial culture and creating an image of Mexico as a place for enterprises with a global impact. In supporting start-ups, Mexico is seeing the world as a potential market for exports by its start-ups and as a source for allies and partners for innovative projects.