Mark | Date Date | Title Title | |||
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04 Jul 2023 |
Guideline No. 497: Defined Approaches on Skin Sensitisation
A Defined Approach (DA) consists of a selection of information sources (e.g in silico predictions, in chemico, in vitro data) used in a specific combination, and resulting data are interpreted using a fixed data interpretation procedure (DIP) (e.g. a... |
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11 Sept 2006 |
Summary of Considerations in the Report from the OECD Expert Groups on Short Term and Long Term Toxicology
|
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24 Feb 1987 |
Test No. 401: Acute Oral Toxicity
The OECD Guidelines for the Testing of Chemicals are a collection of about 100 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of ... |
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09 Oct 2017 |
Test No. 402: Acute Dermal Toxicity
This method provides information on health hazard likely to arise from a short-term exposure to solid or liquid test substance by the dermal route. This Test Guideline is intended primarily for use with rodents (rat, rabbit or guinea pig may be ... |
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25 Jun 2024 |
Test No. 403: Acute Inhalation Toxicity
This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ... |
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28 Jul 2015 |
Test No. 404: Acute Dermal Irritation/Corrosion
This method provides information on health hazard likely to arise from exposure to liquid or solid test substance by dermal application. It recommends sequential testing strategies, which include the performance of validated and accepted in vitro or... |
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04 Jul 2023 |
Test No. 405: Acute Eye Irritation/Corrosion
This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye. This Test Guideline is intended preferably for use with albino rabbit. The test substance is ... |
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30 Jun 2022 |
Test No. 406: Skin Sensitisation
This method provides information on health hazard likely to arise from exposure to test substance via intradermical injection and/or epidermical application. In this Test Guideline, the methods preferred over other are: the Guinea Pig Maximisation ... |
||||
16 Oct 2008 |
Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents
This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The method is based on the repeated oral administration of the substance of interest during one limited period (one dose level ... |
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27 Jun 2018 |
Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents
This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity... |
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21 Sept 1998 |
Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents
This method provides information on health hazard likely to arise from short-term exposure to test substance. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been ... |
||||
12 May 1981 |
Test No. 410: Repeated Dose Dermal Toxicity: 21/28-day Study
This study relates to the analysis, via dermal application, of the health hazard of solid or liquid test substance. This method is composed of two tests: the main test and the limit test. This Test Guideline is intended for use with the adult rat ... |
||||
12 May 1981 |
Test No. 411: Subchronic Dermal Toxicity: 90-day Study
This study relates to the analysis, via dermal application, of the health hazards of solid or liquid test substance. It may be carried out after initial information obtained by acute testing. This method is composed of the main test and the limit ... |
||||
27 Jun 2018 |
Test No. 412: Subacute Inhalation Toxicity: 28-Day Study
This revised Test Guideline 412 (TG 412) has been designed to fully characterize test article toxicity by the inhalation route following repeated exposure for a limited period of time (28 days), and to provide data for quantitative inhalation risk ... |
||||
27 Jun 2018 |
Test No. 413: Subchronic Inhalation Toxicity: 90-day Study
This revised Test Guideline has been designed to fully characterize test article toxicity by the inhalation route for a subchronic duration (90 days), and to provide robust data for quantitative inhalation risk assessments. Groups of 10 male and 10 ... |
||||
27 Jun 2018 |
Test No. 414: Prenatal Developmental Toxicity Study
This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism. The test substance is normally administered to ... |
||||
27 May 1983 |
Test No. 415: One-Generation Reproduction Toxicity Study
This Test Guideline for reproduction testing is designed to provide general information concerning the effects of a test substance (Solid, liquid, gas or vapour) on male and female reproductive performance. The test substance is administered orally ... |
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22 Jan 2001 |
Test No. 416: Two-Generation Reproduction Toxicity
This Test Guideline for two-generation reproduction testing is designed to provide general information concerning the effects of a test substance on the integrity and performance of the male and female reproductive systems, and on the growth and ... |
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23 Jul 2010 |
Test No. 417: Toxicokinetics
This Test Guideline describes in vivo studies that provide information on mass balance, absorption, bioavailability, tissue distribution, metabolism, excretion, and basic toxicokinetic parameters [e.g. AUC], as well as supplemental approaches that ... |
||||
27 Jul 1995 |
Test No. 418: Delayed Neurotoxicity of Organophosphorus Substances Following Acute Exposure
The test substance is administered orally in a single dose to domestic hens. The animals are observed for 21 days, then the remainder of the hens are killed and histopathological examination is undertaken. The young adult domestic laying hen (Gallus ... |
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OECD Guidelines for the Testing of Chemicals, Section 4
Health Effects
The OECD Guidelines for the Testing of Chemicals is a collection of about 150 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of chemicals. They are a set of tools for professionals, used primarily in regulatory safety testing and subsequent chemical and chemical product notification, chemical registration and in chemical evaluation. They can also be used for the selection and ranking of candidate chemicals during the development of new chemicals and products and in toxicology research. This group of tests covers health effects.
English Also available in: French
- ISSN: 20745788 (online)
- https://doi.org/10.1787/20745788
1 - 20 of 86 results
Guideline No. 497: Defined Approaches on Skin Sensitisation
OECD
04 Jul 2023
A Defined Approach (DA) consists of a selection of information sources (e.g in silico predictions, in chemico, in vitro data) used in a specific combination, and resulting data are interpreted using a fixed data interpretation procedure (DIP) (e.g. a...
Summary of Considerations in the Report from the OECD Expert Groups on Short Term and Long Term Toxicology
OECD
11 Sept 2006
Test No. 401: Acute Oral Toxicity
OECD
24 Feb 1987
The OECD Guidelines for the Testing of Chemicals are a collection of about 100 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of ...
Test No. 402: Acute Dermal Toxicity
OECD
09 Oct 2017
This method provides information on health hazard likely to arise from a short-term exposure to solid or liquid test substance by the dermal route. This Test Guideline is intended primarily for use with rodents (rat, rabbit or guinea pig may be ...
Test No. 403: Acute Inhalation Toxicity
OECD
25 Jun 2024
This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...
Test No. 404: Acute Dermal Irritation/Corrosion
OECD
28 Jul 2015
This method provides information on health hazard likely to arise from exposure to liquid or solid test substance by dermal application. It recommends sequential testing strategies, which include the performance of validated and accepted in vitro or...
Test No. 405: Acute Eye Irritation/Corrosion
OECD
04 Jul 2023
This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye. This Test Guideline is intended preferably for use with albino rabbit. The test substance is ...
Test No. 406: Skin Sensitisation
OECD
30 Jun 2022
This method provides information on health hazard likely to arise from exposure to test substance via intradermical injection and/or epidermical application. In this Test Guideline, the methods preferred over other are: the Guinea Pig Maximisation ...
Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents
OECD
16 Oct 2008
This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The method is based on the repeated oral administration of the substance of interest during one limited period (one dose level ...
Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents
OECD
27 Jun 2018
This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity...
Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents
OECD
21 Sept 1998
This method provides information on health hazard likely to arise from short-term exposure to test substance. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been ...
Test No. 410: Repeated Dose Dermal Toxicity: 21/28-day Study
OECD
12 May 1981
This study relates to the analysis, via dermal application, of the health hazard of solid or liquid test substance. This method is composed of two tests: the main test and the limit test. This Test Guideline is intended for use with the adult rat ...
Test No. 411: Subchronic Dermal Toxicity: 90-day Study
OECD
12 May 1981
This study relates to the analysis, via dermal application, of the health hazards of solid or liquid test substance. It may be carried out after initial information obtained by acute testing. This method is composed of the main test and the limit ...
Test No. 412: Subacute Inhalation Toxicity: 28-Day Study
OECD
27 Jun 2018
This revised Test Guideline 412 (TG 412) has been designed to fully characterize test article toxicity by the inhalation route following repeated exposure for a limited period of time (28 days), and to provide data for quantitative inhalation risk ...
Test No. 413: Subchronic Inhalation Toxicity: 90-day Study
OECD
27 Jun 2018
This revised Test Guideline has been designed to fully characterize test article toxicity by the inhalation route for a subchronic duration (90 days), and to provide robust data for quantitative inhalation risk assessments. Groups of 10 male and 10 ...
Test No. 414: Prenatal Developmental Toxicity Study
OECD
27 Jun 2018
This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism. The test substance is normally administered to ...
Test No. 415: One-Generation Reproduction Toxicity Study
OECD
27 May 1983
This Test Guideline for reproduction testing is designed to provide general information concerning the effects of a test substance (Solid, liquid, gas or vapour) on male and female reproductive performance. The test substance is administered orally ...
Test No. 416: Two-Generation Reproduction Toxicity
OECD
22 Jan 2001
This Test Guideline for two-generation reproduction testing is designed to provide general information concerning the effects of a test substance on the integrity and performance of the male and female reproductive systems, and on the growth and ...
Test No. 417: Toxicokinetics
OECD
23 Jul 2010
This Test Guideline describes in vivo studies that provide information on mass balance, absorption, bioavailability, tissue distribution, metabolism, excretion, and basic toxicokinetic parameters [e.g. AUC], as well as supplemental approaches that ...
Test No. 418: Delayed Neurotoxicity of Organophosphorus Substances Following Acute Exposure
OECD
27 Jul 1995
The test substance is administered orally in a single dose to domestic hens. The animals are observed for 21 days, then the remainder of the hens are killed and histopathological examination is undertaken. The young adult domestic laying hen (Gallus ...