Sélectionner | Date Date | Titre Titre | |||
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No. 264 | 19 Jul 2017 |
Guidance Document on Aspects of OECD TG 305 on Fish Bioaccumulation
This Guidance Document addresses aspects of OECD Test Guideline 305 (TG 305) on Fish Bioaccumulation. Following major revisions to TG 305 in 2012, it became clear that separate and detailed guidance was necessary to address complex areas of fish... |
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No. 317 | 31 Aug 2021 |
Guidance Document on Aquatic and Sediment Toxicological Testing of Nanomaterials
This document provides guidance for aquatic (including sediment) ecotoxicity testing of Manufactured Nanomaterials (MNs) to determine their hazard. The definition of MNs as having one dimension between 1 and 100 nm is generally adopted. However, the... |
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16 May 2019 |
Guidance Document on Aquatic Toxicity Testing of Difficult Substances and Mixtures
This document provides the second edition of Guidance Document 23 on Aqueous-Phase Aquatic Toxicity Testing of Difficult Test Chemicals. |
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No. 82 | 24 Oct 2007 |
Guidance Document on Amphibian Histology
The goals of this document are to provide guidance on the collection of morphologic data and preparation of thyroid tissues, from Xenopus laevis, for histopathological analysis to fulfill the needs of the Amphibian Metamorphosis Assay. This document... |
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No. 24 | 10 May 2002 |
Guidance Document on Acute Oral Toxicity Testing
This Guidance Document provides information for both the regulated community and regulators to assist with the choice of the most appropriate Guideline to enable particular data requirements to be met while reducing the number of animals used and... |
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No. 344 | 08 Dec 2021 |
Guidance Document for the scientific review of Adverse Outcome Pathways
The Adverse Outcome Pathway (AOP) framework has been developed to facilitate the collection of mechanistic information derived from toxicological science in a structured manner, to assist in establishing causal relationships between molecular and... |
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No. 260 | 10 Mar 2017 |
Guidance Document for the Use of Adverse Outcome Pathways in Developing Integrated Approaches to Testing and Assessment (IATA)
The OECD has been developing guidance documents and tools for the use of alternative methods such as (Q)SAR, chemical categories and Adverse Outcome Pathways (AOPs) as a part of Integrated Approaches for Testing and Assessment (IATA). However, there... |
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No. 318 | 20 Jul 2020 |
Guidance Document for the Testing of Dissolution and Dispersion Stability of Nanomaterials, and the Use of the Data for Further Environmental Testing and Assessment
This document provides guidance for the methods to address dissolution rate and dispersion stability for nanomaterials with focus on environmental aqueous media. The definition of nanomaterials as having one dimension between 1 and 100 nm is... |
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No. 22 | 10 May 2002 |
Guidance Document for the Performance Of Out-door Monolith Lysimeter Studies
This document provides guidance for the performance of out-door monolith lysimeter studies. |
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No. 1 | 10 May 2002 |
Guidance Document for the Development of OECD Guidelines for Testing of Chemicals
This Monograph describes in detail the process of Test Guideline development, including the structure of the Test Guidelines Programme, the responsibilities of those involved and the procedures which should be followed. |
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No. 9 | 10 May 2002 |
Guidance Document for the Conduct of Studies of Occupational Exposure to Pesticides During Agricultural Application
This Guidance Document presents an internationally harmonized approach to the conduct of studies of occupational exposure to pesticides during agricultural application. |
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No. 28 | 01 Nov 2004 |
Guidance Document for the Conduct of Skin Absorption Studies
This guidance document has been prepared to support technical aspects of the OECD skin absorption test guidelines. In particular is discusses the various aspects of in vivo vs. in vitro testing. |
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No. 20 | 26 Nov 2004 |
Guidance Document for Neurotoxicity Testing
This document is intended to provide guidance on strategies and methods for testing of chemicals for potential neurotoxicity. The primary objective of this guidance is to ensure that necessary and sufficient data are obtained to enable adequate... |
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No. 106 | 28 Jul 2009 |
Guidance Document for Histologic Evaluation of Endocrine and Reproductive Tests in Rodents
This Guidance Document has been prepared to provide the pathologist reading slides from endocrine and reproductive studies (eg the updated TG407 and longer studies) with sufficient information to be able to identify the often subtle histopathologic... |
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No. 185 | 25 Apr 2013 |
Guidance Document for Exposure Assessment Based on Environmental Monitoring Data
This document provides guidance for performing an exposure assessment – for humans and the environment – based on environmental monitoring data. It covers topics such as environmental levels and distribution of contaminants, ways of using monitoring... |
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No. 211 | 13 Apr 2017 |
Guidance Document for Describing Non-Guideline In Vitro Test Methods
The purpose of this guidance is to harmonise the way non-guideline in vitro methods are described and thereby facilitate an assessment of the relevance of test methods for biological activities and responses of interest, and an assessment of the... |
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08 Mar 1995 |
Guidance Document for Aquatic Effects Assessment
This document results from an OECD project on Aquatic Effects Assessment. In the scheme developed in the document, information on the toxicity of a chemical is used to derive a Maximum Tolerable Concentration (MTG) in water, i.e. the maximum... |
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No. 117 | 27 Jul 2011 |
Guidance Document 117 on the Current Implementation of Internal Triggers in Test Guideline 443 for an Extended One Generation Reproductive Toxicity Study, in the United States and Canada
This document constitutes an essential supplement to OECD Test Guideline 443 (EOGRTS) to describe the use of data gathered within the study to determine if a second generation should be produced. However, as a starting point, available mode of action... |
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No. 116 | 03 Sept 2014 |
Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453
This guidance provides additional information on the conduct of studies performed using Test Guidelines 451, 452 and Test Guideline 453. |
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No. 229 | 13 Apr 2017 |
Fundamental And Guiding Principles For (Q)SAR Analysis Of Chemical Carcinogens with Mechanistic Considerations
In this document the importance of mechanistic consideration in quantitative structure-activity relationship ((Q)SAR) analysis, the critical role of mechanistic consideration in improving various (Q)SAR approaches and possible integrative approaches... |
OECD Series on Testing and Assessment
This Series includes publications related to testing and assessment of chemicals; some of them support the development of OECD Test Guidelines (e.g. validation reports, guidance documents, detailed review papers).
Anglais
- ISSN : 20777876 (en ligne)
- https://doi.org/10.1787/20777876
81 - 100 of 144 results
Guidance Document on Aspects of OECD TG 305 on Fish Bioaccumulation
OCDE
19 Jul 2017
This Guidance Document addresses aspects of OECD Test Guideline 305 (TG 305) on Fish Bioaccumulation. Following major revisions to TG 305 in 2012, it became clear that separate and detailed guidance was necessary to address complex areas of fish...
This document provides guidance for aquatic (including sediment) ecotoxicity testing of Manufactured Nanomaterials (MNs) to determine their hazard. The definition of MNs as having one dimension between 1 and 100 nm is generally adopted. However, the...
This document provides the second edition of Guidance Document 23 on Aqueous-Phase Aquatic Toxicity Testing of Difficult Test Chemicals.
Guidance Document on Amphibian Histology
OCDE
24 Oct 2007
The goals of this document are to provide guidance on the collection of morphologic data and preparation of thyroid tissues, from Xenopus laevis, for histopathological analysis to fulfill the needs of the Amphibian Metamorphosis Assay. This document...
Guidance Document on Acute Oral Toxicity Testing
OCDE
10 May 2002
This Guidance Document provides information for both the regulated community and regulators to assist with the choice of the most appropriate Guideline to enable particular data requirements to be met while reducing the number of animals used and...
The Adverse Outcome Pathway (AOP) framework has been developed to facilitate the collection of mechanistic information derived from toxicological science in a structured manner, to assist in establishing causal relationships between molecular and...
Guidance Document for the Use of Adverse Outcome Pathways in Developing Integrated Approaches to Testing and Assessment (IATA)
OCDE
10 Mar 2017
The OECD has been developing guidance documents and tools for the use of alternative methods such as (Q)SAR, chemical categories and Adverse Outcome Pathways (AOPs) as a part of Integrated Approaches for Testing and Assessment (IATA). However, there...
This document provides guidance for the methods to address dissolution rate and dispersion stability for nanomaterials with focus on environmental aqueous media. The definition of nanomaterials as having one dimension between 1 and 100 nm is...
This document provides guidance for the performance of out-door monolith lysimeter studies.
This Monograph describes in detail the process of Test Guideline development, including the structure of the Test Guidelines Programme, the responsibilities of those involved and the procedures which should be followed.
Guidance Document for the Conduct of Studies of Occupational Exposure to Pesticides During Agricultural Application
OCDE
10 May 2002
This Guidance Document presents an internationally harmonized approach to the conduct of studies of occupational exposure to pesticides during agricultural application.
Guidance Document for the Conduct of Skin Absorption Studies
OCDE
01 Nov 2004
This guidance document has been prepared to support technical aspects of the OECD skin absorption test guidelines. In particular is discusses the various aspects of in vivo vs. in vitro testing.
Guidance Document for Neurotoxicity Testing
OCDE
26 Nov 2004
This document is intended to provide guidance on strategies and methods for testing of chemicals for potential neurotoxicity. The primary objective of this guidance is to ensure that necessary and sufficient data are obtained to enable adequate...
Guidance Document for Histologic Evaluation of Endocrine and Reproductive Tests in Rodents
OCDE
28 Jul 2009
This Guidance Document has been prepared to provide the pathologist reading slides from endocrine and reproductive studies (eg the updated TG407 and longer studies) with sufficient information to be able to identify the often subtle histopathologic...
This document provides guidance for performing an exposure assessment – for humans and the environment – based on environmental monitoring data. It covers topics such as environmental levels and distribution of contaminants, ways of using monitoring...
Guidance Document for Describing Non-Guideline In Vitro Test Methods
OCDE
13 Apr 2017
The purpose of this guidance is to harmonise the way non-guideline in vitro methods are described and thereby facilitate an assessment of the relevance of test methods for biological activities and responses of interest, and an assessment of the...
Guidance Document for Aquatic Effects Assessment
OCDE
08 Mar 1995
This document results from an OECD project on Aquatic Effects Assessment. In the scheme developed in the document, information on the toxicity of a chemical is used to derive a Maximum Tolerable Concentration (MTG) in water, i.e. the maximum...
This document constitutes an essential supplement to OECD Test Guideline 443 (EOGRTS) to describe the use of data gathered within the study to determine if a second generation should be produced. However, as a starting point, available mode of action...
Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453
OCDE
03 Sept 2014
This guidance provides additional information on the conduct of studies performed using Test Guidelines 451, 452 and Test Guideline 453.
Fundamental And Guiding Principles For (Q)SAR Analysis Of Chemical Carcinogens with Mechanistic Considerations
OCDE
13 Apr 2017
In this document the importance of mechanistic consideration in quantitative structure-activity relationship ((Q)SAR) analysis, the critical role of mechanistic consideration in improving various (Q)SAR approaches and possible integrative approaches...