Sélectionner | Date Date | Titre Titre | |||
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No. 238 | 13 Apr 2017 |
Overview on genetic toxicology TGs
Following a general update of the Genetic Toxicology TGs in 2015, the present Document was written to provide succinct and useful information to individuals unfamiliar with genetic toxicology testing, as well as experienced individuals wishing to... |
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No. 237 | 13 Apr 2017 |
Guidance Document on Considerations for Waiving or Bridging of Mammalian Acute Toxicity Tests
Acute toxicity tests are an area of focus for developing alternative assays and approaches to address animal welfare concerns. In the context of this document, acute toxicity studies refer to studies involving a single exposure to a test chemical and... |
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No. 230 | 13 Apr 2017 |
OECD Guidance for Characterising Hydrocarbon Solvents for Assessment Purposes
This document presents a harmonized method for characterising, for assessment purposes, a specific subcategory of UVCBs (Substances of Unknown or Variable composition, Complex reaction products or Biological materials): hydrocarbon solvent... |
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No. 229 | 13 Apr 2017 |
Fundamental And Guiding Principles For (Q)SAR Analysis Of Chemical Carcinogens with Mechanistic Considerations
In this document the importance of mechanistic consideration in quantitative structure-activity relationship ((Q)SAR) analysis, the critical role of mechanistic consideration in improving various (Q)SAR approaches and possible integrative approaches... |
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No. 222 | 24 Aug 2015 |
Performance Standards for the Human Recombinant Estrogen Receptor Binding Assay
This document is intended as a guide to developers of new test methods that are analogous to existing, fully validated test methods in that they are based on similar scientific principles and predict the same effect(colloquially referred to as “me... |
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No. 220 | 23 Jul 2015 |
Performance Standards for the Assessment of Proposed Similar or Modified In Vitro Reconstructed Human Epidermis (RhE) Test Methods for Skin Irritation Testing as described in TG 439
The purpose of Performance Standards (PS) is to provide the basis by which new similar or modified test methods, both proprietary (i.e. copyrighted, trademarked, registered) and non-proprietary,can be deemed to be structurally and mechanistically... |
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No. 219 | 23 Jul 2015 |
Performance Standards for the Assessment of Proposed Similar or Modified In Vitro Reconstructed Human Epidermis (RHE) Test Methods for Skin Corrosion Testing as described in TG 431
The purpose of Performance Standards (PS) is to provide the basis by which new similar or modified test methods, both proprietary (i.e. copyrighted, trademarked, registered) and non-proprietary,can be deemed to be structurally and mechanistically... |
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No. 218 | 04 Aug 2015 |
Performance Standards for the Assessment of Proposed Similar or Modified In Vitro Reconstructed Human Epidermis (RHE) Test Methods for Skin Corrosion Testing as described in TG 430
The purpose of Performance Standards (PS) is to provide the basis by which new similar or modified test methods, both proprietary (i.e. copyrighted, trademarked, registered) and non-proprietary, can be deemed to be structurally and mechanistically... |
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No. 215 | 13 Apr 2017 |
Report of the Workshop on a Framework for the Development and Use Of Integrated Approaches to Testing and Assessment
This document is a report of the Workshop on a framework for the development and use of integrated approaches to testing and assessment which was held on 17-19 November 2014 in Crystal City VA, USA. This framework should provide guiding principles,... |
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No. 214 | 22 May 2015 |
Guidance Document on the In Vitro Syrian Hamster Embryo (SHE) Cell Transformation Assay
This document presents guidance for conducting the Syrian Hamster Embryo Cells Transformation Assay (SHE CTA). The purpose of this Guidance document is to allow the regulatory community to use the described method as part of a weight of evidence... |
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No. 213 | 22 May 2015 |
Performance Standards for Assessment of Proposed Similar or Modified In Vitro Skin Sensitisation ARE-NRF2 Luciferase Test Methods
The purpose of PS is to provide the basis by which new or modified test methods, both proprietary (i.e. copyrighted, trademarked, registered) and non-proprietary can demonstrate to have sufficient reliability and relevance for specific testing... |
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No. 212 | 13 Apr 2017 |
Guidance on Selecting a Strategy for Assessing the Ecological risk of Organometallic and Organic Metal Salt Substances based on their Environmental Fate
In this document a strategy is presented to facilitate the ecological risk assessment of organometallic compounds (OM) and organic metal salts (OMS), outlining key steps that are based on elucidation of the fate of these substances in the... |
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No. 211 | 13 Apr 2017 |
Guidance Document for Describing Non-Guideline In Vitro Test Methods
The purpose of this guidance is to harmonise the way non-guideline in vitro methods are described and thereby facilitate an assessment of the relevance of test methods for biological activities and responses of interest, and an assessment of the... |
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No. 207 | 11 Jul 2014 |
New Scoping Document on in vitro and ex vivo Assays for the Identification of Modulators of Thyroid Hormone Signalling
This scoping document aims at bringing forward relevant in vitro and ex vivo thyroid assays to the attention of OECD member countries, to provide recommendations for their development/use, and also, to identify aspects/blocks of the thyroid... |
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No. 203 | 13 Apr 2017 |
Guidance Document on an Integrated Approach on Testing and Assessment (IATA) for Skin Corrosion and Irritation
This Guidance Document proposes an integrated approach on testing and assessment (IATA) for skin corrosion and irritation. It also provides consistent information on key characteristics of each of the individual information sources of the IATA, and... |
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No. 201 | 11 Jul 2014 |
Guidance Document on Harpacticoid Copepod Development and Reproduction Test with Amphiascus
This Guidance Document describes test procedures for measuring the (sub)chronic effects of chemicals on an estuarine/marine harpacticoid copepod species under semistatic conditions; the biological endpoints include survival and development rates of... |
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No. 194 | 13 Apr 2017 |
Guidance on Grouping of Chemicals, Second Edition
This guidance document is part of the OECD effort to provide guidance for assessing the hazards of chemical substances while gaining efficiencies and improving animal welfare. The approach described in this guidance document is to consider closely... |
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No. 193 | 13 Apr 2017 |
OECD Guidance for Characterising Oleochemical Substances for Assessment Purposes
This document presents a harmonized method for characterising, for assessment purposes, a specific subcategory of UVCBs (Substances of Unknown or Variable composition, Complex reaction products or Biological materials): oleochemical substances. Many... |
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No. 185 | 25 Apr 2013 |
Guidance Document for Exposure Assessment Based on Environmental Monitoring Data
This document provides guidance for performing an exposure assessment – for humans and the environment – based on environmental monitoring data. It covers topics such as environmental levels and distribution of contaminants, ways of using monitoring... |
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No. 178 | 21 Aug 2012 |
Detailed Review Paper on the State of the Science on Novel In Vitro and In Vivo Screening and Testing Methods and Endpoints for Evaluating Endocrine Disruptors
This paper provides methods for both the mechanistic evaluation of the action of Endocrine Disrupter Chemicals (EDCs). |
OECD Series on Testing and Assessment
This Series includes publications related to testing and assessment of chemicals; some of them support the development of OECD Test Guidelines (e.g. validation reports, guidance documents, detailed review papers).
Anglais
- ISSN : 20777876 (en ligne)
- https://doi.org/10.1787/20777876
41 - 60 of 144 results
Overview on genetic toxicology TGs
OCDE
13 Apr 2017
Following a general update of the Genetic Toxicology TGs in 2015, the present Document was written to provide succinct and useful information to individuals unfamiliar with genetic toxicology testing, as well as experienced individuals wishing to...
Guidance Document on Considerations for Waiving or Bridging of Mammalian Acute Toxicity Tests
OCDE
13 Apr 2017
Acute toxicity tests are an area of focus for developing alternative assays and approaches to address animal welfare concerns. In the context of this document, acute toxicity studies refer to studies involving a single exposure to a test chemical and...
This document presents a harmonized method for characterising, for assessment purposes, a specific subcategory of UVCBs (Substances of Unknown or Variable composition, Complex reaction products or Biological materials): hydrocarbon solvent...
Fundamental And Guiding Principles For (Q)SAR Analysis Of Chemical Carcinogens with Mechanistic Considerations
OCDE
13 Apr 2017
In this document the importance of mechanistic consideration in quantitative structure-activity relationship ((Q)SAR) analysis, the critical role of mechanistic consideration in improving various (Q)SAR approaches and possible integrative approaches...
This document is intended as a guide to developers of new test methods that are analogous to existing, fully validated test methods in that they are based on similar scientific principles and predict the same effect(colloquially referred to as “me...
The purpose of Performance Standards (PS) is to provide the basis by which new similar or modified test methods, both proprietary (i.e. copyrighted, trademarked, registered) and non-proprietary,can be deemed to be structurally and mechanistically...
The purpose of Performance Standards (PS) is to provide the basis by which new similar or modified test methods, both proprietary (i.e. copyrighted, trademarked, registered) and non-proprietary,can be deemed to be structurally and mechanistically...
The purpose of Performance Standards (PS) is to provide the basis by which new similar or modified test methods, both proprietary (i.e. copyrighted, trademarked, registered) and non-proprietary, can be deemed to be structurally and mechanistically...
Report of the Workshop on a Framework for the Development and Use Of Integrated Approaches to Testing and Assessment
OCDE
13 Apr 2017
This document is a report of the Workshop on a framework for the development and use of integrated approaches to testing and assessment which was held on 17-19 November 2014 in Crystal City VA, USA. This framework should provide guiding principles,...
Guidance Document on the In Vitro Syrian Hamster Embryo (SHE) Cell Transformation Assay
OCDE
22 May 2015
This document presents guidance for conducting the Syrian Hamster Embryo Cells Transformation Assay (SHE CTA). The purpose of this Guidance document is to allow the regulatory community to use the described method as part of a weight of evidence...
Performance Standards for Assessment of Proposed Similar or Modified In Vitro Skin Sensitisation ARE-NRF2 Luciferase Test Methods
OCDE
22 May 2015
The purpose of PS is to provide the basis by which new or modified test methods, both proprietary (i.e. copyrighted, trademarked, registered) and non-proprietary can demonstrate to have sufficient reliability and relevance for specific testing...
Guidance on Selecting a Strategy for Assessing the Ecological risk of Organometallic and Organic Metal Salt Substances based on their Environmental Fate
OCDE
13 Apr 2017
In this document a strategy is presented to facilitate the ecological risk assessment of organometallic compounds (OM) and organic metal salts (OMS), outlining key steps that are based on elucidation of the fate of these substances in the...
Guidance Document for Describing Non-Guideline In Vitro Test Methods
OCDE
13 Apr 2017
The purpose of this guidance is to harmonise the way non-guideline in vitro methods are described and thereby facilitate an assessment of the relevance of test methods for biological activities and responses of interest, and an assessment of the...
New Scoping Document on in vitro and ex vivo Assays for the Identification of Modulators of Thyroid Hormone Signalling
OCDE
11 Jul 2014
This scoping document aims at bringing forward relevant in vitro and ex vivo thyroid assays to the attention of OECD member countries, to provide recommendations for their development/use, and also, to identify aspects/blocks of the thyroid...
Guidance Document on an Integrated Approach on Testing and Assessment (IATA) for Skin Corrosion and Irritation
OCDE
13 Apr 2017
This Guidance Document proposes an integrated approach on testing and assessment (IATA) for skin corrosion and irritation. It also provides consistent information on key characteristics of each of the individual information sources of the IATA, and...
Guidance Document on Harpacticoid Copepod Development and Reproduction Test with Amphiascus
OCDE
11 Jul 2014
This Guidance Document describes test procedures for measuring the (sub)chronic effects of chemicals on an estuarine/marine harpacticoid copepod species under semistatic conditions; the biological endpoints include survival and development rates of...
Guidance on Grouping of Chemicals, Second Edition
OCDE
13 Apr 2017
This guidance document is part of the OECD effort to provide guidance for assessing the hazards of chemical substances while gaining efficiencies and improving animal welfare. The approach described in this guidance document is to consider closely...
This document presents a harmonized method for characterising, for assessment purposes, a specific subcategory of UVCBs (Substances of Unknown or Variable composition, Complex reaction products or Biological materials): oleochemical substances. Many...
This document provides guidance for performing an exposure assessment – for humans and the environment – based on environmental monitoring data. It covers topics such as environmental levels and distribution of contaminants, ways of using monitoring...
This paper provides methods for both the mechanistic evaluation of the action of Endocrine Disrupter Chemicals (EDCs).