Sélectionner | Date Date | Titre Titre | |||
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No. 129 | 20 Jul 2010 |
Guidance Document on Using Cytotoxicity Tests to Estimate Starting Doses for Acute Oral Systematic Toxicity Tests
This Guidance Document describes methods to determine the in vitro basal cytotoxicity of test substances using NRU assays and the use of the in vitro data to determine starting doses for in vivo acute oral systemic toxicity tests. The NRU assay is... |
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No. 203 | 13 Apr 2017 |
Guidance Document on an Integrated Approach on Testing and Assessment (IATA) for Skin Corrosion and Irritation
This Guidance Document proposes an integrated approach on testing and assessment (IATA) for skin corrosion and irritation. It also provides consistent information on key characteristics of each of the individual information sources of the IATA, and... |
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No. 342 | 28 Jul 2021 |
Guidance Document on testing Nanomaterials using OECD TG No. 312 “Leaching in soil columns"
This document provides specific guidance for test preparation, implementation, performance, analysis and reporting using the OECD TG No. 312 for testing the mobility and retention of NMs in different types of soils. The GD is likely also relevant for... |
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No. 148 | 08 Aug 2017 |
Guidance Document on the Androgenised Female Stickleback Screen
This guidance document describes an in vivo screening assay where sexually mature female sticklebacks are exposed to suspected anti-androgenic chemicals during a limited part of their life-cycle (21 days). The AFFS can detect both androgens and... |
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No. 56 | 31 Jul 2006 |
Guidance Document on the Breakdown of Organic Matter in Litter Bags
The purpose of this Guidance Document is to identify possible and suitable approaches to the evaluation of chemicals impact, and in particular plant protection products’ impact, on soil organic matter breakdown. The test method and procedures... |
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No. 160 | 06 Jul 2018 |
Guidance Document on the Collection of Eyes Tissues for Histological Evaluation and Collection of Data - Second Edition
This Guidance Document accompanies the OECD Test Guideline (TG) 437 on the bovine corneal opacity and permeability (BCOP) test method and TG 438 on the isolated chicken eye (ICE) test method. It provides users with guidelines for collecting... |
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No. 122 | 07 Jun 2010 |
Guidance Document on the Determination of the Toxicity of a Test Chemical to the Dung Beetle Aphodius Constans
This document presents the OECD Guidance Document on the Determination of the Toxicity of a Test Chemical to the Dung Beetle Aphodius Constans. This test method is designed to assess the effects of a test chemical, e.g. veterinary pharmaceuticals, to... |
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No. 123 | 31 May 2010 |
Guidance Document on the Diagnosis of Endocrine-related Histopathology in Fish Gonads
Exposure of fathead minnow (Pimephales promelas), Japanese medaka (Oryzias latipes) and zebrafish (Danio rerio) to endocrine disrupting chemicals may result in histopathological alterations of gonadal structure and microarchitecture. The diagnosis of... |
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No. 75 | 03 Sept 2014 |
Guidance Document on the Honey Bee (Apis Mellifera L.) Brood test Under Semi-field Conditions
The method described in this guidance document assesses the effects of plant protection products (PPPs), and has been validated using the active Fenoxycarb, which is known to act as an insect growth regulator (IGR), to the honey bee brood (Apis... |
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No. 214 | 22 May 2015 |
Guidance Document on the In Vitro Syrian Hamster Embryo (SHE) Cell Transformation Assay
This document presents guidance for conducting the Syrian Hamster Embryo Cells Transformation Assay (SHE CTA). The purpose of this Guidance document is to allow the regulatory community to use the described method as part of a weight of evidence... |
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No. 19 | 10 May 2002 |
Guidance Document on the Recognition, Assessment and Use of Clinical Signs as Human Endpoints for Experimental Animals Used in Safety Evaluation
The purpose of this Guidance Document is to apply the principles of the Three Rs to the use of animals in regulatory toxicity tests. |
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No. 256 | 11 Jul 2017 |
Guidance Document on the Reporting of Defined Approaches and Individual Information Sources to be Used within Integrated Approaches to Testing and Assessment (IATA) for Skin Sensitisation
With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides guidance on the reporting of defined approaches to testing... |
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No. 255 | 13 Apr 2017 |
Guidance Document on the Reporting of Defined Approaches to be Used Within Integrated Approaches to Testing and Assessment
With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides a set of principles for reporting defined approaches to... |
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No. 45 | 01 Nov 2004 |
Guidance Document on the Use of Multimedia Models for Estimating Overall Environmental Persistance and Long-Range Transport
This Guidance Document concerns using multimedia models, i.e. generic evaluative models that can calculate overall environmental persistence (Pov) and potential for long-range transport (LTRP) covering multiple compartments such as air, water,... |
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No. 27 | 10 May 2002 |
Guidance Document on the Use of the Harmonised System for the Classification of Chemicals which are Hazardous for the Aquatic Environment
This document provides a description of a Harmonised System for the Classification of Chemicals which are Hazardous for the Aquatic Environment and guidance to how the system will work. |
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No. 71 | 19 Jul 2017 |
Guidance Document on the Uterothrophic Bioassay - Procedure to Test for Antioestrogenicity
This Guidance document focuses on the antioestrogenic protocol; it is the outcome of the experience gained during the validation test programme and the results obtained thereby with the use of a strong oestrogen receptor antagonist. Due to... |
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No. 34 | 18 Aug 2005 |
Guidance Document on the Validation and International Acceptance of New or Updated Test Methods for Hazard Assessment
The purpose of this document is to provide guidance on issues related to the validation of new or updated test methods consistent with current approaches. This document provides a synopsis of the current state of test method validation, in what is a... |
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No. 69 | 03 Sept 2014 |
Guidance Document on the Validation of (Quantitative) Structure-Activity Relationship [(Q)SAR] Models
This document presents principles and helpful guides for validating (Q)SAR technology for a variety of applications. |
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No. 35 | 12 Dec 2002 |
Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies
These Guidance Notes outline core concepts in order to obviate the need to consult large numbers of text books, while still pointing the reader to sources of more detailed or specific information. |
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No. 32 | 10 May 2002 |
Guidance Notes for Analysis and Evaluation of Repeat-Dose Toxicity Studies
This document presents a general guide to the analysis and evaluation of data from studies involving repeated exposures of toxicity test species to pesticides and other chemicals. |
OECD Series on Testing and Assessment
This Series includes publications related to testing and assessment of chemicals; some of them support the development of OECD Test Guidelines (e.g. validation reports, guidance documents, detailed review papers).
Anglais
- ISSN : 20777876 (en ligne)
- https://doi.org/10.1787/20777876
81 - 100 of 155 results
Guidance Document on Using Cytotoxicity Tests to Estimate Starting Doses for Acute Oral Systematic Toxicity Tests
OCDE
20 Jul 2010
This Guidance Document describes methods to determine the in vitro basal cytotoxicity of test substances using NRU assays and the use of the in vitro data to determine starting doses for in vivo acute oral systemic toxicity tests. The NRU assay is...
Guidance Document on an Integrated Approach on Testing and Assessment (IATA) for Skin Corrosion and Irritation
OCDE
13 Apr 2017
This Guidance Document proposes an integrated approach on testing and assessment (IATA) for skin corrosion and irritation. It also provides consistent information on key characteristics of each of the individual information sources of the IATA, and...
Guidance Document on testing Nanomaterials using OECD TG No. 312 “Leaching in soil columns"
OCDE
28 Jul 2021
This document provides specific guidance for test preparation, implementation, performance, analysis and reporting using the OECD TG No. 312 for testing the mobility and retention of NMs in different types of soils. The GD is likely also relevant for...
Guidance Document on the Androgenised Female Stickleback Screen
OCDE
08 Aug 2017
This guidance document describes an in vivo screening assay where sexually mature female sticklebacks are exposed to suspected anti-androgenic chemicals during a limited part of their life-cycle (21 days). The AFFS can detect both androgens and...
Guidance Document on the Breakdown of Organic Matter in Litter Bags
OCDE
31 Jul 2006
The purpose of this Guidance Document is to identify possible and suitable approaches to the evaluation of chemicals impact, and in particular plant protection products’ impact, on soil organic matter breakdown. The test method and procedures...
Guidance Document on the Collection of Eyes Tissues for Histological Evaluation and Collection of Data - Second Edition
OCDE
06 Jul 2018
This Guidance Document accompanies the OECD Test Guideline (TG) 437 on the bovine corneal opacity and permeability (BCOP) test method and TG 438 on the isolated chicken eye (ICE) test method. It provides users with guidelines for collecting...
Guidance Document on the Determination of the Toxicity of a Test Chemical to the Dung Beetle Aphodius Constans
OCDE
07 Jun 2010
This document presents the OECD Guidance Document on the Determination of the Toxicity of a Test Chemical to the Dung Beetle Aphodius Constans. This test method is designed to assess the effects of a test chemical, e.g. veterinary pharmaceuticals, to...
Guidance Document on the Diagnosis of Endocrine-related Histopathology in Fish Gonads
OCDE
31 May 2010
Exposure of fathead minnow (Pimephales promelas), Japanese medaka (Oryzias latipes) and zebrafish (Danio rerio) to endocrine disrupting chemicals may result in histopathological alterations of gonadal structure and microarchitecture. The diagnosis of...
Guidance Document on the Honey Bee (Apis Mellifera L.) Brood test Under Semi-field Conditions
OCDE
03 Sept 2014
The method described in this guidance document assesses the effects of plant protection products (PPPs), and has been validated using the active Fenoxycarb, which is known to act as an insect growth regulator (IGR), to the honey bee brood (Apis...
Guidance Document on the In Vitro Syrian Hamster Embryo (SHE) Cell Transformation Assay
OCDE
22 May 2015
This document presents guidance for conducting the Syrian Hamster Embryo Cells Transformation Assay (SHE CTA). The purpose of this Guidance document is to allow the regulatory community to use the described method as part of a weight of evidence...
Guidance Document on the Recognition, Assessment and Use of Clinical Signs as Human Endpoints for Experimental Animals Used in Safety Evaluation
OCDE
10 May 2002
The purpose of this Guidance Document is to apply the principles of the Three Rs to the use of animals in regulatory toxicity tests.
With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides guidance on the reporting of defined approaches to testing...
Guidance Document on the Reporting of Defined Approaches to be Used Within Integrated Approaches to Testing and Assessment
OCDE
13 Apr 2017
With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides a set of principles for reporting defined approaches to...
Guidance Document on the Use of Multimedia Models for Estimating Overall Environmental Persistance and Long-Range Transport
OCDE
01 Nov 2004
This Guidance Document concerns using multimedia models, i.e. generic evaluative models that can calculate overall environmental persistence (Pov) and potential for long-range transport (LTRP) covering multiple compartments such as air, water,...
Guidance Document on the Use of the Harmonised System for the Classification of Chemicals which are Hazardous for the Aquatic Environment
OCDE
10 May 2002
This document provides a description of a Harmonised System for the Classification of Chemicals which are Hazardous for the Aquatic Environment and guidance to how the system will work.
Guidance Document on the Uterothrophic Bioassay - Procedure to Test for Antioestrogenicity
OCDE
19 Jul 2017
This Guidance document focuses on the antioestrogenic protocol; it is the outcome of the experience gained during the validation test programme and the results obtained thereby with the use of a strong oestrogen receptor antagonist. Due to...
Guidance Document on the Validation and International Acceptance of New or Updated Test Methods for Hazard Assessment
OCDE
18 Aug 2005
The purpose of this document is to provide guidance on issues related to the validation of new or updated test methods consistent with current approaches. This document provides a synopsis of the current state of test method validation, in what is a...
Guidance Document on the Validation of (Quantitative) Structure-Activity Relationship [(Q)SAR] Models
OCDE
03 Sept 2014
This document presents principles and helpful guides for validating (Q)SAR technology for a variety of applications.
Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies
OCDE
12 Dec 2002
These Guidance Notes outline core concepts in order to obviate the need to consult large numbers of text books, while still pointing the reader to sources of more detailed or specific information.
This document presents a general guide to the analysis and evaluation of data from studies involving repeated exposures of toxicity test species to pesticides and other chemicals.