Sélectionner | Date Date | Titre Titre | |||
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No. 82 | 24 Oct 2007 |
Guidance Document on Amphibian Histology
The goals of this document are to provide guidance on the collection of morphologic data and preparation of thyroid tissues, from Xenopus laevis, for histopathological analysis to fulfill the needs of the Amphibian Metamorphosis Assay. This document... |
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16 May 2019 |
Guidance Document on Aquatic Toxicity Testing of Difficult Substances and Mixtures
This document provides the second edition of Guidance Document 23 on Aqueous-Phase Aquatic Toxicity Testing of Difficult Test Chemicals. |
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No. 317 | 31 Aug 2021 |
Guidance Document on Aquatic and Sediment Toxicological Testing of Nanomaterials
This document provides guidance for aquatic (including sediment) ecotoxicity testing of Manufactured Nanomaterials (MNs) to determine their hazard. The definition of MNs as having one dimension between 1 and 100 nm is generally adopted. However, the... |
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No. 264 | 19 Jul 2017 |
Guidance Document on Aspects of OECD TG 305 on Fish Bioaccumulation
This Guidance Document addresses aspects of OECD Test Guideline 305 (TG 305) on Fish Bioaccumulation. Following major revisions to TG 305 in 2012, it became clear that separate and detailed guidance was necessary to address complex areas of fish... |
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No. 237 | 13 Apr 2017 |
Guidance Document on Considerations for Waiving or Bridging of Mammalian Acute Toxicity Tests
Acute toxicity tests are an area of focus for developing alternative assays and approaches to address animal welfare concerns. In the context of this document, acute toxicity studies refer to studies involving a single exposure to a test chemical and... |
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No. 7 | 10 May 2002 |
Guidance Document on Direct Phototransformation of Chemicals in Water
This document situates three proposals for a test guidelines on direct phototransformation in water in a broad context. |
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No. 286 | 10 Dec 2018 |
Guidance Document on Good In Vitro Method Practices (GIVIMP)
In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing,... |
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No. 201 | 11 Jul 2014 |
Guidance Document on Harpacticoid Copepod Development and Reproduction Test with Amphiascus
This Guidance Document describes test procedures for measuring the (sub)chronic effects of chemicals on an estuarine/marine harpacticoid copepod species under semistatic conditions; the biological endpoints include survival and development rates of... |
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No. 125 | 01 Jun 2010 |
Guidance Document on Histopathology for Inhalation Toxicity Studies, Supporting TG 412 (Subacute Inhalation Toxicity: 28-day Study) and TG 413 (Subchronic Inhalation Toxicity: 90-day Study)
The purpose of this Guidance Document (GD) is to provide pathologists, toxicologists, and associated scientists with recommended guidelines for performing the pathology tasks required by the specifications of TG 412 and 413, and for optimising the... |
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No. 332 | 16 Jul 2021 |
Guidance Document on Honey Bee (Apis mellifera L.) Homing Flight Test, using single oral exposure to sub-lethal doses of test chemical
This guidance document presents a standardised test evaluating the ability of honeybees (Apis mellifera) exposed to a single dose of test chemical to return to the hive; it is a semi-field test, where dietary exposure to the test chemical and bee... |
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No. 239 | 15 Jul 2016 |
Guidance Document on Honey Bee Larval Toxicity Test following Repeated Exposure
This document describes a honey bee brood laboratory toxicity test using repeated doses. It is based on the OECD Test Guideline 237: Honey bees (Apis mellifera) larval toxicity test, single exposure (1) ring tested in seven European laboratories,... |
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No. 39 | 06 Jul 2018 |
Guidance Document on Inhalation Toxicity Studies - Second edition
The main purpose of this document is to assist the regulated community and regulators in selecting the most appropriate acute inhalation TG so that particular data requirements can be met while reducing animal usage and suffering. This Guidance... |
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No. 97 | 29 Jul 2008 |
Guidance Document on Magnitude of Pesticide Residues in Processed Commodities
A wide range of raw agricultural commodities (RAC) are processed before consumption by the public. In fact, many RACs are consumed in multiple processed forms [e.g. grapes (RAC), raisins, grape juice, wine; potato (RAC), chips, cooked, baked and... |
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No. 43 | 24 Jul 2008 |
Guidance Document on Mammalian Reproductive Toxicity Testing and Assessment
This document is intended to provide guidance on methodological aspects, interpretation of data and an overall approach for testing of chemicals for potential human and other mammalian reproductive toxicity. The document constitutes an essential... |
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No. 42 | 01 Nov 2004 |
Guidance Document on Reporting Summary Information on Environmental, Occupational and Consumer Exposure
This document contains guidance for using the summary exposure information reporting formats, which were developed by the OECD Ad Hoc Group on Reporting Summary Exposure Information. |
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No. 53 | 02 May 2006 |
Guidance Document on Simulated Freshwater Lentic Field Tests (Outdoor Microcosms and Mesocosms)
Outdoor microcosms and mesocosms are useful in risk assessment when lower-tier and higher-tier laboratory studies (single-species and multi-species) indicate potential risks. They can be an important tool in bridging the gap between these studies and... |
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No. 29 | 10 May 2002 |
Guidance Document on Transformation/Dissolution of Metals and Metal Compounds in Aqueous Media
This Test Guidance is designed to determine the rate and extent to which metals and sparingly soluble metal compounds can produce soluble available ionic and other metal-bearing species in aqueous media. |
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No. 129 | 20 Jul 2010 |
Guidance Document on Using Cytotoxicity Tests to Estimate Starting Doses for Acute Oral Systematic Toxicity Tests
This Guidance Document describes methods to determine the in vitro basal cytotoxicity of test substances using NRU assays and the use of the in vitro data to determine starting doses for in vivo acute oral systemic toxicity tests. The NRU assay is... |
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No. 203 | 13 Apr 2017 |
Guidance Document on an Integrated Approach on Testing and Assessment (IATA) for Skin Corrosion and Irritation
This Guidance Document proposes an integrated approach on testing and assessment (IATA) for skin corrosion and irritation. It also provides consistent information on key characteristics of each of the individual information sources of the IATA, and... |
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No. 342 | 28 Jul 2021 |
Guidance Document on testing Nanomaterials using OECD TG No. 312 “Leaching in soil columns"
This document provides specific guidance for test preparation, implementation, performance, analysis and reporting using the OECD TG No. 312 for testing the mobility and retention of NMs in different types of soils. The GD is likely also relevant for... |
OECD Series on Testing and Assessment
This Series includes publications related to testing and assessment of chemicals; some of them support the development of OECD Test Guidelines (e.g. validation reports, guidance documents, detailed review papers).
Anglais
- ISSN : 20777876 (en ligne)
- https://doi.org/10.1787/20777876
61 - 80 of 144 results
Guidance Document on Amphibian Histology
OCDE
24 Oct 2007
The goals of this document are to provide guidance on the collection of morphologic data and preparation of thyroid tissues, from Xenopus laevis, for histopathological analysis to fulfill the needs of the Amphibian Metamorphosis Assay. This document...
This document provides the second edition of Guidance Document 23 on Aqueous-Phase Aquatic Toxicity Testing of Difficult Test Chemicals.
This document provides guidance for aquatic (including sediment) ecotoxicity testing of Manufactured Nanomaterials (MNs) to determine their hazard. The definition of MNs as having one dimension between 1 and 100 nm is generally adopted. However, the...
Guidance Document on Aspects of OECD TG 305 on Fish Bioaccumulation
OCDE
19 Jul 2017
This Guidance Document addresses aspects of OECD Test Guideline 305 (TG 305) on Fish Bioaccumulation. Following major revisions to TG 305 in 2012, it became clear that separate and detailed guidance was necessary to address complex areas of fish...
Guidance Document on Considerations for Waiving or Bridging of Mammalian Acute Toxicity Tests
OCDE
13 Apr 2017
Acute toxicity tests are an area of focus for developing alternative assays and approaches to address animal welfare concerns. In the context of this document, acute toxicity studies refer to studies involving a single exposure to a test chemical and...
This document situates three proposals for a test guidelines on direct phototransformation in water in a broad context.
Guidance Document on Good In Vitro Method Practices (GIVIMP)
OCDE
10 Dec 2018
In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing,...
Guidance Document on Harpacticoid Copepod Development and Reproduction Test with Amphiascus
OCDE
11 Jul 2014
This Guidance Document describes test procedures for measuring the (sub)chronic effects of chemicals on an estuarine/marine harpacticoid copepod species under semistatic conditions; the biological endpoints include survival and development rates of...
The purpose of this Guidance Document (GD) is to provide pathologists, toxicologists, and associated scientists with recommended guidelines for performing the pathology tasks required by the specifications of TG 412 and 413, and for optimising the...
Guidance Document on Honey Bee (Apis mellifera L.) Homing Flight Test, using single oral exposure to sub-lethal doses of test chemical
OCDE
16 Jul 2021
This guidance document presents a standardised test evaluating the ability of honeybees (Apis mellifera) exposed to a single dose of test chemical to return to the hive; it is a semi-field test, where dietary exposure to the test chemical and bee...
This document describes a honey bee brood laboratory toxicity test using repeated doses. It is based on the OECD Test Guideline 237: Honey bees (Apis mellifera) larval toxicity test, single exposure (1) ring tested in seven European laboratories,...
Guidance Document on Inhalation Toxicity Studies - Second edition
OCDE
06 Jul 2018
The main purpose of this document is to assist the regulated community and regulators in selecting the most appropriate acute inhalation TG so that particular data requirements can be met while reducing animal usage and suffering. This Guidance...
A wide range of raw agricultural commodities (RAC) are processed before consumption by the public. In fact, many RACs are consumed in multiple processed forms [e.g. grapes (RAC), raisins, grape juice, wine; potato (RAC), chips, cooked, baked and...
This document is intended to provide guidance on methodological aspects, interpretation of data and an overall approach for testing of chemicals for potential human and other mammalian reproductive toxicity. The document constitutes an essential...
Guidance Document on Reporting Summary Information on Environmental, Occupational and Consumer Exposure
OCDE
01 Nov 2004
This document contains guidance for using the summary exposure information reporting formats, which were developed by the OECD Ad Hoc Group on Reporting Summary Exposure Information.
Guidance Document on Simulated Freshwater Lentic Field Tests (Outdoor Microcosms and Mesocosms)
OCDE
02 May 2006
Outdoor microcosms and mesocosms are useful in risk assessment when lower-tier and higher-tier laboratory studies (single-species and multi-species) indicate potential risks. They can be an important tool in bridging the gap between these studies and...
Guidance Document on Transformation/Dissolution of Metals and Metal Compounds in Aqueous Media
OCDE
10 May 2002
This Test Guidance is designed to determine the rate and extent to which metals and sparingly soluble metal compounds can produce soluble available ionic and other metal-bearing species in aqueous media.
Guidance Document on Using Cytotoxicity Tests to Estimate Starting Doses for Acute Oral Systematic Toxicity Tests
OCDE
20 Jul 2010
This Guidance Document describes methods to determine the in vitro basal cytotoxicity of test substances using NRU assays and the use of the in vitro data to determine starting doses for in vivo acute oral systemic toxicity tests. The NRU assay is...
Guidance Document on an Integrated Approach on Testing and Assessment (IATA) for Skin Corrosion and Irritation
OCDE
13 Apr 2017
This Guidance Document proposes an integrated approach on testing and assessment (IATA) for skin corrosion and irritation. It also provides consistent information on key characteristics of each of the individual information sources of the IATA, and...
Guidance Document on testing Nanomaterials using OECD TG No. 312 “Leaching in soil columns"
OCDE
28 Jul 2021
This document provides specific guidance for test preparation, implementation, performance, analysis and reporting using the OECD TG No. 312 for testing the mobility and retention of NMs in different types of soils. The GD is likely also relevant for...