Sélectionner | Date Date | Titre Titre | |||
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No. 17 | 10 May 2002 |
Environmental Exposure Assessment Strategies for Existing Industrial Chemicals in OECD Member Countries
This paper reviews some general strategies used by OECD Member countries when assessing exposure in the context of risk assessments for existing industrial chemicals. |
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No. 351 | 17 Jun 2022 |
Establishing Occupational Exposure Limits
Occupational exposure limits (OELs) are derived internationally by many government agencies and professional organisations. The absence of a globally harmonised approach contributes towards differences in derivation approaches and resulting OEL... |
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No. 306 | 23 Jul 2019 |
Estimating Mouthing Exposure in Children – Compilation of Case Studies
Children can be more vulnerable than adults to environmental hazards, such as those presented by chemicals, due to their physiological differences and unique behaviours. Considering global concern for children’s health, the OECD has been working to... |
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No. 177 | 03 Sept 2014 |
Fish Toxicity Testing Framework
This document presents a review of fish toxicity testing for the regulatory purpose of chemical safety. The main focus is on fish toxicity, but fish bioaccumulation is also considered where relevant. |
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No. 229 | 13 Apr 2017 |
Fundamental And Guiding Principles For (Q)SAR Analysis Of Chemical Carcinogens with Mechanistic Considerations
In this document the importance of mechanistic consideration in quantitative structure-activity relationship ((Q)SAR) analysis, the critical role of mechanistic consideration in improving various (Q)SAR approaches and possible integrative approaches... |
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No. 116 | 03 Sept 2014 |
Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453
This guidance provides additional information on the conduct of studies performed using Test Guidelines 451, 452 and Test Guideline 453. |
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No. 117 | 27 Jul 2011 |
Guidance Document 117 on the Current Implementation of Internal Triggers in Test Guideline 443 for an Extended One Generation Reproductive Toxicity Study, in the United States and Canada
This document constitutes an essential supplement to OECD Test Guideline 443 (EOGRTS) to describe the use of data gathered within the study to determine if a second generation should be produced. However, as a starting point, available mode of action... |
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08 Mar 1995 |
Guidance Document for Aquatic Effects Assessment
This document results from an OECD project on Aquatic Effects Assessment. In the scheme developed in the document, information on the toxicity of a chemical is used to derive a Maximum Tolerable Concentration (MTG) in water, i.e. the maximum... |
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No. 211 | 13 Apr 2017 |
Guidance Document for Describing Non-Guideline In Vitro Test Methods
The purpose of this guidance is to harmonise the way non-guideline in vitro methods are described and thereby facilitate an assessment of the relevance of test methods for biological activities and responses of interest, and an assessment of the... |
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No. 185 | 25 Apr 2013 |
Guidance Document for Exposure Assessment Based on Environmental Monitoring Data
This document provides guidance for performing an exposure assessment – for humans and the environment – based on environmental monitoring data. It covers topics such as environmental levels and distribution of contaminants, ways of using monitoring... |
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No. 106 | 28 Jul 2009 |
Guidance Document for Histologic Evaluation of Endocrine and Reproductive Tests in Rodents
This Guidance Document has been prepared to provide the pathologist reading slides from endocrine and reproductive studies (eg the updated TG407 and longer studies) with sufficient information to be able to identify the often subtle histopathologic... |
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No. 20 | 26 Nov 2004 |
Guidance Document for Neurotoxicity Testing
This document is intended to provide guidance on strategies and methods for testing of chemicals for potential neurotoxicity. The primary objective of this guidance is to ensure that necessary and sufficient data are obtained to enable adequate... |
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No. 28 | 01 Nov 2004 |
Guidance Document for the Conduct of Skin Absorption Studies
This guidance document has been prepared to support technical aspects of the OECD skin absorption test guidelines. In particular is discusses the various aspects of in vivo vs. in vitro testing. |
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No. 9 | 10 May 2002 |
Guidance Document for the Conduct of Studies of Occupational Exposure to Pesticides During Agricultural Application
This Guidance Document presents an internationally harmonized approach to the conduct of studies of occupational exposure to pesticides during agricultural application. |
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No. 1 | 10 May 2002 |
Guidance Document for the Development of OECD Guidelines for Testing of Chemicals
This Monograph describes in detail the process of Test Guideline development, including the structure of the Test Guidelines Programme, the responsibilities of those involved and the procedures which should be followed. |
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No. 22 | 10 May 2002 |
Guidance Document for the Performance Of Out-door Monolith Lysimeter Studies
This document provides guidance for the performance of out-door monolith lysimeter studies. |
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No. 318 | 20 Jul 2020 |
Guidance Document for the Testing of Dissolution and Dispersion Stability of Nanomaterials, and the Use of the Data for Further Environmental Testing and Assessment
This document provides guidance for the methods to address dissolution rate and dispersion stability for nanomaterials with focus on environmental aqueous media. The definition of nanomaterials as having one dimension between 1 and 100 nm is... |
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No. 260 | 10 Mar 2017 |
Guidance Document for the Use of Adverse Outcome Pathways in Developing Integrated Approaches to Testing and Assessment (IATA)
The OECD has been developing guidance documents and tools for the use of alternative methods such as (Q)SAR, chemical categories and Adverse Outcome Pathways (AOPs) as a part of Integrated Approaches for Testing and Assessment (IATA). However, there... |
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No. 344 | 08 Dec 2021 |
Guidance Document for the scientific review of Adverse Outcome Pathways
The Adverse Outcome Pathway (AOP) framework has been developed to facilitate the collection of mechanistic information derived from toxicological science in a structured manner, to assist in establishing causal relationships between molecular and... |
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No. 24 | 10 May 2002 |
Guidance Document on Acute Oral Toxicity Testing
This Guidance Document provides information for both the regulated community and regulators to assist with the choice of the most appropriate Guideline to enable particular data requirements to be met while reducing the number of animals used and... |
OECD Series on Testing and Assessment
This Series includes publications related to testing and assessment of chemicals; some of them support the development of OECD Test Guidelines (e.g. validation reports, guidance documents, detailed review papers).
Anglais
- ISSN : 20777876 (en ligne)
- https://doi.org/10.1787/20777876
41 - 60 of 144 results
Environmental Exposure Assessment Strategies for Existing Industrial Chemicals in OECD Member Countries
OCDE
10 May 2002
This paper reviews some general strategies used by OECD Member countries when assessing exposure in the context of risk assessments for existing industrial chemicals.
Establishing Occupational Exposure Limits
OCDE
17 Jun 2022
Occupational exposure limits (OELs) are derived internationally by many government agencies and professional organisations. The absence of a globally harmonised approach contributes towards differences in derivation approaches and resulting OEL...
Children can be more vulnerable than adults to environmental hazards, such as those presented by chemicals, due to their physiological differences and unique behaviours. Considering global concern for children’s health, the OECD has been working to...
Fish Toxicity Testing Framework
OCDE
03 Sept 2014
This document presents a review of fish toxicity testing for the regulatory purpose of chemical safety. The main focus is on fish toxicity, but fish bioaccumulation is also considered where relevant.
Fundamental And Guiding Principles For (Q)SAR Analysis Of Chemical Carcinogens with Mechanistic Considerations
OCDE
13 Apr 2017
In this document the importance of mechanistic consideration in quantitative structure-activity relationship ((Q)SAR) analysis, the critical role of mechanistic consideration in improving various (Q)SAR approaches and possible integrative approaches...
Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453
OCDE
03 Sept 2014
This guidance provides additional information on the conduct of studies performed using Test Guidelines 451, 452 and Test Guideline 453.
This document constitutes an essential supplement to OECD Test Guideline 443 (EOGRTS) to describe the use of data gathered within the study to determine if a second generation should be produced. However, as a starting point, available mode of action...
Guidance Document for Aquatic Effects Assessment
OCDE
08 Mar 1995
This document results from an OECD project on Aquatic Effects Assessment. In the scheme developed in the document, information on the toxicity of a chemical is used to derive a Maximum Tolerable Concentration (MTG) in water, i.e. the maximum...
Guidance Document for Describing Non-Guideline In Vitro Test Methods
OCDE
13 Apr 2017
The purpose of this guidance is to harmonise the way non-guideline in vitro methods are described and thereby facilitate an assessment of the relevance of test methods for biological activities and responses of interest, and an assessment of the...
This document provides guidance for performing an exposure assessment – for humans and the environment – based on environmental monitoring data. It covers topics such as environmental levels and distribution of contaminants, ways of using monitoring...
Guidance Document for Histologic Evaluation of Endocrine and Reproductive Tests in Rodents
OCDE
28 Jul 2009
This Guidance Document has been prepared to provide the pathologist reading slides from endocrine and reproductive studies (eg the updated TG407 and longer studies) with sufficient information to be able to identify the often subtle histopathologic...
Guidance Document for Neurotoxicity Testing
OCDE
26 Nov 2004
This document is intended to provide guidance on strategies and methods for testing of chemicals for potential neurotoxicity. The primary objective of this guidance is to ensure that necessary and sufficient data are obtained to enable adequate...
Guidance Document for the Conduct of Skin Absorption Studies
OCDE
01 Nov 2004
This guidance document has been prepared to support technical aspects of the OECD skin absorption test guidelines. In particular is discusses the various aspects of in vivo vs. in vitro testing.
Guidance Document for the Conduct of Studies of Occupational Exposure to Pesticides During Agricultural Application
OCDE
10 May 2002
This Guidance Document presents an internationally harmonized approach to the conduct of studies of occupational exposure to pesticides during agricultural application.
This Monograph describes in detail the process of Test Guideline development, including the structure of the Test Guidelines Programme, the responsibilities of those involved and the procedures which should be followed.
This document provides guidance for the performance of out-door monolith lysimeter studies.
This document provides guidance for the methods to address dissolution rate and dispersion stability for nanomaterials with focus on environmental aqueous media. The definition of nanomaterials as having one dimension between 1 and 100 nm is...
Guidance Document for the Use of Adverse Outcome Pathways in Developing Integrated Approaches to Testing and Assessment (IATA)
OCDE
10 Mar 2017
The OECD has been developing guidance documents and tools for the use of alternative methods such as (Q)SAR, chemical categories and Adverse Outcome Pathways (AOPs) as a part of Integrated Approaches for Testing and Assessment (IATA). However, there...
The Adverse Outcome Pathway (AOP) framework has been developed to facilitate the collection of mechanistic information derived from toxicological science in a structured manner, to assist in establishing causal relationships between molecular and...
Guidance Document on Acute Oral Toxicity Testing
OCDE
10 May 2002
This Guidance Document provides information for both the regulated community and regulators to assist with the choice of the most appropriate Guideline to enable particular data requirements to be met while reducing the number of animals used and...