Browse by: "2022"

This Detailed Review Paper (DRP) aims to present and discuss the application and interpretation of in vitro immunotoxicity assays, mainly covering immunosuppression, and to define an in vitro tiered approach to testing and assessment. A well-functioning immune system is essential for maintaining the integrity of an organism. Immune cells are an integral part of other systems including the respiratory, dermal, gastrointestinal, neurological, cardiovascular, reproductive, hepatobiliary, musculoskeletal system, and endocrine systems. As such, exposure to immunotoxic compounds can have serious adverse health consequences affecting responses to both communicable and non-communicable diseases. It is therefore important to understand the immunotoxic potential of xenobiotics and the risk(s) they pose to humans.

The bacterial reverse gene mutation test described in OECD Test Guideline 471 is the most widely used in vitro test for the detection of mutagenicity. The standard format utilises plate incorporation and/or preincubation method; a test mixture containing bacteria, test chemical, S9-mix, when required, and agar, is plated on 90- to 100-mm plates. Several miniaturised versions of the assay have been developed and are already in use, particularly for early screening of new products, as during research and development, large numbers of chemicals have to be tested that are often only available in low amounts. The primary advantage of these miniaturised versions is a significant reduction of the amount of test material needed to conduct the experiments; some may also allow simultaneous analyses of large number of samples, increasing throughput and reducing resources and cost. The aim of this Detailed Review Paper (DRP) was to evaluate the performance of several types of miniaturised assays, relative to the standard bacterial reverse gene mutation test specified in OECD TG 471. Performance evaluations were based on a retrospective analysis of data provided by well-established genotoxicity testing laboratories.

The Dubai Health Authority of the United Arab Emirates has requested technical assistance from the OECD to assess the state of the health information infrastructure and support the creation and implementation of a Health System Performance Assessment framework.

Digital government has become a priority for Luxembourg as a means to enable its public sector to deliver more responsive and trusted services. The Digital Government Review of Luxembourg evaluates the efforts made by the government to transition towards a digital government approach. It provides in-depth analysis and policy recommendations to improve institutional governance, digital investments, digital talent and skills, government service delivery and the strategic use of data. Its findings can help Luxembourg achieve a more digitally mature and data-driven administration to better serve citizens and businesses.

Digital Services: Supporting SMEs to get Tax Right, by the OECD Forum on Tax Administration (FTA), is the third report in the FTA’s Supporting SMEs to Get Tax Right Series. This report looks at how digital services can help SMEs comply with their tax obligations, leading to reduced burdens and increased compliance rates. In addition to a number of examples from tax administrations, the report also highlights two detailed case studies. The report was developed by the Canada Revenue Agency with the support of the Forum on Tax Administration’s Community of Interest on SMEs.

This Digital Trade Review of Brazil provides an overview of Brazil’s participation in digital trade and the related regulatory environment. It provides insights into how Brazil might ensure that the new challenges raised by the digital transformation for trade can be managed and the benefits shared more inclusively. While Brazil has embraced the digital transformation and has strong potential to benefit from digital trade, it will need to continue the ongoing process of regulatory reform. This includes reducing tariff and non-tariff barriers to trade on ICT goods; reducing regulatory barriers to ICT services; increasing engagement in international discussions on digital trade; and continuing efforts to bridge digital divides.

Direct air capture plays an important and growing role in net zero pathways. Capturing CO2 directly from the air and permanently storing it removes the CO2 from the atmosphere, providing a way to balance emissions that are difficult to avoid, including from long-distance transport and heavy industry, as well as offering a solution for legacy emissions. Air-captured CO2 can also be used as a climate-neutral feedstock for a range of products that require a source of carbon. In the IEA Net Zero Emissions by 2050 Scenario, direct air capture technologies capture more than 85 Mt of CO2 in 2030 and around 980 MtCO2 in 2050, requiring a large and accelerated scale-up from almost 0.01 MtCO2 today. Currently 18 direct air capture facilities are operating in Canada, Europe and the United States. The first large-scale direct air capture plant of up to 1 MtCO2/year is in advanced development and is expected to be operating in the United States by the mid-2020s. This report explores the growing momentum behind direct air capture, together with the opportunities and challenges for scaling up the deployment of direct air capture technologies consistent with net zero goals. It considers the current status of these technologies, their potential for cost reductions, their future energy needs, and the optimal locations for direct air capture facilities. Finally, the report identifies the key drivers for direct air capture investment and priorities for policy action.

One in seven working-age adults identifies as having a disability in OECD countries, a share that is also substantial and growing among young people (8% in 2019). Many of them are excluded from meaningful work and have low levels of income and social engagement. This report documents the current labour market situation of people with disability, who continue to face large employment, unemployment and poverty gaps compared with people without disability. The report concludes that the goal set up some twenty years ago of making disability policies pro-active and employment-oriented has not been achieved. In particular, key areas of disability policy have received too little attention so far, such as policies to support young people with disability, improve the skills of people with disability, and intervene early in the course of a health problem or disability. The report calls for rigorous disability mainstreaming in all relevant policies and practices as the missing link to better labour market inclusion.

One in seven working‑age adults identifies as having a disability in OECD countries. Many of them are excluded from meaningful work and have low levels of income and social engagement. Becoming sick or disabled often leads people to leave the labour market even if they still can and want to work. Governments can help create an environment that supports a return‑to‑work for such people. This report reviews the Slovenian sickness and disability system and proposes recommendations to promote the employment of people with disability. Frequent long-term sickness absences are a growing issue in Slovenia, in part due to the design of the sickness insurance programme: workers falling ill get relatively high payments, for an unlimited time, with no activation or return-to-work offers. This report shows that intervening early is key to preventing sickness claimants from exiting the labour force. For this to occur, employers and occupational experts have to be involved sooner than at present, in a structured vocational rehabilitation process. Sickness insurance reform should provide the right work incentives, align sickness and disability assessment for long-term sickness claimants, and cap the maximum sickness benefit payment period. Cooperation between all key stakeholders in different phases of the process is critical. Such cooperation will allow the much-needed creation of a joint body responsible for the assessment of sickness, disability and vocational rehabilitation needs.

There is a discernible and growing gap between the qualifications that a university degree certifies and the actual generic, 21st-century skills with which students graduate from higher education. By generic skills, it is meant literacy and critical thinking skills encompassing problem solving, analytic reasoning and communications competency. As automation takes over non- and lower-cognitive tasks in today’s workplace, these generic skills are especially valued but a tertiary degree is a poor indicator of skills level. In the United States, the Council for Aid for Education developed an assessment of generic skills called the CLA+ and carried out testing in six countries between 2016 and 2021. This book provides the data and analysis of this “CLA+ International Initiative”.

Nigeria is one of the largest recipients of international philanthropic funding, but little is known about its domestic philanthropy, receiving approximately USD 192 million per year from large international foundations between 2013-18. However, these estimates do not consider funding from domestic foundations, as information on local philanthropy is limited. The report offers a first insight into a selection of domestic foundations in Nigeria. It contrasts these findings with other sources of development finance, including international philanthropy and official development assistance (ODA) targeting the country. However, only 12 of 56 foundations invited to participate responded to the survey. The low response rate and resulting small sample do not allow for generalisations about the domestic philanthropic sector in the country. Funding from 12 domestic philanthropic organisations in Nigeria amounted to USD 89 million over 2013-18. Three foundations provided the bulk of these funds (70%): MTN Nigeria Foundation, Partnership Initiatives in the Niger Delta (PIND) and TY Danjuma Foundation. Most domestic giving was allocated to health and reproductive health (USD 28 million), government and civil society (USD 25 million) and education (USD 22 million). Within the health sector, the most supported areas were basic health care, reproductive care, and prevention of noncommunicable diseases. Funding towards government and civil society prioritised conflict resolution, human rights and support to women’s rights organisations.

Trust in public institutions is a cornerstone of the Norwegian administrative and political model. It has also been a crucial element in Norway’s response to the COVID-19 pandemic. Preserving and strengthening this “trust capital” will be essential for Norway in addressing future trade-offs and challenges, such as ensuring the sustainability of the welfare model, coping with climate change and maintaining social cohesion. Based on the results of the OECD Survey on Drivers of Trust in Public Institutions and using a combination of quantitative and qualitative methods, this study examines the main determinants of trust in Norway’s national government, local government and public administration.

As “market referees”, regulators contribute to the delivery of essential public services. Their organisational culture, behaviour and governance are important factors in how regulators, and the sectors they oversee, perform. The OECD Performance Assessment Framework for Economic Regulators (PAFER) looks at the institutions, processes and practices that can create an organisational culture of performance and results. The report uses PAFER to assess elements linked to both the internal and external governance of Peru’s Water and Sanitation Services Regulator (Superintendencia Nacional de Servicios de Saneamiento, Sunass). The review acknowledges the technical expertise of Sunass within the institutional framework, analyses the key drivers of its performance, and identifies a number of opportunities to help the regulator prepare for the future, including in the context of sector-wide challenges and the COVID-19 crisis.

Society’s dependence on space infrastructure is at a critical juncture. Public and private actors worldwide are planning to launch tens of thousands of satellites into Earth’s orbit in the next five years. This will greatly expand and enrich the use of space resources, but it will also result in more crowded orbits and greater risk of damage from satellite collision and space debris. As satellite launches continue to multiply and concerns grow, the long-term sustainability of space-based infrastructure on orbit and beyond is set to emerge as an increasingly important space policy issue of the 21st century. This publication takes stock of the growing socio-economic dependence of our modern societies on space assets, and the general threats to space-based infrastructure from debris in particular. Notably, it provides fresh insights into the value of space-based infrastructure and the potential costs generated by space debris, drawing on new academic research developed especially for the OECD project on the economics of space sustainability.

The Economic Outlook for Southeast Asia, China and India is a regular publication on regional economic growth and development in Emerging Asia. It focuses on the economic conditions of Association of Southeast Asian Nations (ASEAN) members: Brunei Darussalam, Cambodia, Indonesia, Lao PDR, Malaysia, Myanmar, the Philippines, Singapore, Thailand and Viet Nam, as well as China and India. It comprises two main parts. The first part presents the regional economic monitor, depicting the economic outlook and macroeconomic challenges in the region. The second part consists of special thematic chapters addressing a major issue facing the region. The 2022 edition addresses financing sustainable recovery from the COVID-19 pandemic. The COVID-19 pandemic is proving to be extremely costly, both economically and socially and sustainable financing solutions are crucial for an equitable and inclusive recovery. The report explores how governments can obtain additional financing by harnessing bond markets, and use green, social and sustainability bonds to achieve policy objectives.

The effects of Russia’s invasion of Ukraine (with its dramatic impact on energy and food prices), the continuation of the COVID-19 pandemic, and extreme weather events in some parts of the world in 2022 are expected to reverberate into 2023. International implications for education and training include economic uncertainty and tight labour markets, ongoing digital transformation, and continued growth and influence of mass information. These trends challenge education policymakers to transform existing pathways in their countries and economies, so people can become effective lifelong learners to navigate change. Building on the OECD’s Framework of Responsiveness and Resilience in Education Policy, as well as analysis of international policies and practices from over 40 education systems implemented mainly since 2020, this report identifies three areas of policy effort that education policymakers can undertake in 2023: 1) enhancing the relevance of learning pathways; 2) easing transitions throughout learners’ pathways; and 3) nurturing learners’ aspirations. Lessons emerging from recent policy efforts are synthesised into key policy pointers for 2023. The report has been prepared with evidence from the Education Policy Outlook series—the OECD’s analytical observatory of education policy.