Sélectionner | Date Date | Titre Titre | |||
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No. 25 | 10 May 2002 |
Detailed Review Document on Hazard Classification Systems for Specific Target Organ Systemic Toxicity Following Single or Repeated Exposure in OECD Member Countries
This detailed review document examines member country hazard classification systems for specific target organ systemic toxicity following single or repeated exposure. |
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No. 121 | 03 Sept 2014 |
Detailed Review Paper (DRP) on Molluscs Life-cycle Toxicity Testing
This paper reviews what is known about the responses of molluscs to endocrine disrupting chemicals (EDCs), to consider whether it would be desirable and feasible to standardise mollusc-based partial- and full-lifecycle tests that are sensitive to... |
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No. 21 | 10 May 2002 |
Detailed Review Paper Appraisal of Test Methods for Sex Hormone Disrupting Chemicals
This documents servies as the basis for the first step in the consideration and development of OECD Test Guidelines for the testing of chemicals for endocrine-disrupting effects. |
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No. 74 | 13 Aug 2017 |
Detailed Review Paper for Avian Two-generation Toxicity Testing
This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of avian endocrinology, with a particular focus on the evaluation of possible endocrine disruption in birds in two-generation tests. The content of... |
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No. 46 | 01 Nov 2004 |
Detailed Review Paper on Amphibian Metamorphosis Assay for the Detection of Thyroid Active Substances
This Detailed Review Paper (DRP) provides the current state-of-the-knowledge in the area of amphibian metamorphosis with the view to use amphibian metamorphosis as a model for the detection of chemicals affecting the thyroid axis in vertebrates. |
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No. 55 | 31 Jul 2006 |
Detailed Review Paper on Aquatic Arthropods in Life Cycle Toxicity Tests with an Emphasis on Developmental, Reproductive and Endocrine Disruptive Effects
This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of aquatic invertebrate endocrinology, with a particular focus on the evaluation of possible developmental reproductive and endocrine disruptive... |
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No. 11 | 10 May 2002 |
Detailed Review Paper on Aquatic Testing Methods for Pesticides and Industrial Chemicals
This review paper is based on the compilation of more than 600 pelagic and benthic testing methods. |
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No. 2 | 12 Dec 2002 |
Detailed Review Paper on Biodegradability Testing
This document reviews the area of biodegradability testing in order to identify whether, in the light of scientific developments, there was a need to revise existing OECD Test Guidelines or to develop new Guidelines. |
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No. 31 | 13 Aug 2007 |
Detailed Review Paper on Cell Transformation Assays for Detection of Chemical Carcinogens
In vivo rodent models remain the only reliable way for experimental investigation of the carcinogenic risk of chemicals to humans, however, the rodent carcinogenicity assay is expensive and time-consuming. Several in vitro alternatives to... |
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No. 135 | 16 Sept 2010 |
Detailed Review Paper on Environmental Endocrine Disruptor Screening: The Use of Estrogen and Androgen Receptor Binding and Transactivation Assays in Fish
The current Detailed Review Paper (DRP) has been developed under the Validation Management Groups for Ecotoxicity Testing (VMGeco) and Non-Animal testing (VMG NA). The DRP focuses on estrogen and androgen in vitro receptor and transcriptional... |
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No. 95 | 25 Jul 2008 |
Detailed Review Paper on Fish Life-Cycle Tests
The principal purpose of this Detailed Review Paper (DRP) is to define the basis, objectives and conduct of fish life-cycle tests for the effects of endocrine disrupting chemicals (EDCs). The main focus is on four species of fish (fathead minnow... |
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No. 47 | 01 Nov 2004 |
Detailed Review Paper on Fish Screening Assays for the Detection of Endocrine Active Substances
This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of fish screening assays for chemicals active at the endocrine level on the reproductive system of test animals. |
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No. 360 | 19 Sept 2022 |
Detailed Review Paper on In Vitro Test Addressing Immunotoxicity With a Focus on Immunosuppression
This Detailed Review Paper (DRP) aims to present and discuss the application and interpretation of in vitro immunotoxicity assays, mainly covering immunosuppression, and to define an in vitro tiered approach to testing and assessment. A... |
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No. 57 | 02 Aug 2006 |
Detailed Review Paper on Thyroid Hormone Disruption Assays
This document reviews the state of assays for thyroid toxicants across four vertebrate classes (fish, amphibians, birds and mammals) within the context of a thorough review of thyroid endocrinology across these taxa. Considering the similarity of the... |
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No. 103 | 23 Jul 2009 |
Detailed Review Paper on Transgenic Rodent Mutation Assays
Induced chromosomal and gene mutations cause genetic diseases, birth defects and other disease conditions and play a role in carcinogenesis. While it is widely accepted that in vivo mutation assays are more relevant to the human condition than in... |
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No. 178 | 21 Aug 2012 |
Detailed Review Paper on the State of the Science on Novel In Vitro and In Vivo Screening and Testing Methods and Endpoints for Evaluating Endocrine Disruptors
This paper provides methods for both the mechanistic evaluation of the action of Endocrine Disrupter Chemicals (EDCs). |
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No. 97 | 03 Sept 2014 |
Detailed Review Paper on the Use of Metabolising Systems for In Vitro Testing of Endocrine Disruptors
This Detailed Review Paper describes some endocrine pathways that have been shown to be susceptible to environmental endocrine disruption and whose disruption could contribute to increasing incidents of some disorders in humans and wildlife populations. |
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No. 358 | 19 Sept 2022 |
Detailed Review Paper on the miniaturised versions of the bacterial reverse gene mutation test
The bacterial reverse gene mutation test described in OECD Test Guideline 471 is the most widely used in vitro test for the detection of mutagenicity. The standard format utilises plate incorporation and/or preincubation method; a test mixture... |
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No. 381 | 24 Jul 2023 |
Detailed review paper (DRP) on the thyroid hormone system in fish and identification of potential thyroid hormone system related endpoints for inclusion in existing OECD fish Test Guidelines
International standardised test guidelines (TGs) with sensitive endpoints form the basis for hazard identification and characterisation and risk assessment used in the regulation of chemicals. The OECD has developed the Conceptual Framework for the... |
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No. 343 | 21 Sept 2021 |
Detailed review paper on the Retinoid System
The aim of this document is to provide a more detailed overview of the understanding of the role of retinoid signalling in several organ systems for which more information may be known, as well as evaluate potential gaps in knowledge, and identify... |
OECD Series on Testing and Assessment
This Series includes publications related to testing and assessment of chemicals; some of them support the development of OECD Test Guidelines (e.g. validation reports, guidance documents, detailed review papers).
Anglais
- ISSN : 20777876 (en ligne)
- https://doi.org/10.1787/20777876
21 - 40 of 144 results
This detailed review document examines member country hazard classification systems for specific target organ systemic toxicity following single or repeated exposure.
Detailed Review Paper (DRP) on Molluscs Life-cycle Toxicity Testing
OCDE
03 Sept 2014
This paper reviews what is known about the responses of molluscs to endocrine disrupting chemicals (EDCs), to consider whether it would be desirable and feasible to standardise mollusc-based partial- and full-lifecycle tests that are sensitive to...
Detailed Review Paper Appraisal of Test Methods for Sex Hormone Disrupting Chemicals
OCDE
10 May 2002
This documents servies as the basis for the first step in the consideration and development of OECD Test Guidelines for the testing of chemicals for endocrine-disrupting effects.
Detailed Review Paper for Avian Two-generation Toxicity Testing
OCDE
13 Aug 2017
This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of avian endocrinology, with a particular focus on the evaluation of possible endocrine disruption in birds in two-generation tests. The content of...
Detailed Review Paper on Amphibian Metamorphosis Assay for the Detection of Thyroid Active Substances
OCDE
01 Nov 2004
This Detailed Review Paper (DRP) provides the current state-of-the-knowledge in the area of amphibian metamorphosis with the view to use amphibian metamorphosis as a model for the detection of chemicals affecting the thyroid axis in vertebrates.
Detailed Review Paper on Aquatic Arthropods in Life Cycle Toxicity Tests with an Emphasis on Developmental, Reproductive and Endocrine Disruptive Effects
OCDE
31 Jul 2006
This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of aquatic invertebrate endocrinology, with a particular focus on the evaluation of possible developmental reproductive and endocrine disruptive...
Detailed Review Paper on Aquatic Testing Methods for Pesticides and Industrial Chemicals
OCDE
10 May 2002
This review paper is based on the compilation of more than 600 pelagic and benthic testing methods.
Detailed Review Paper on Biodegradability Testing
OCDE
12 Dec 2002
This document reviews the area of biodegradability testing in order to identify whether, in the light of scientific developments, there was a need to revise existing OECD Test Guidelines or to develop new Guidelines.
Detailed Review Paper on Cell Transformation Assays for Detection of Chemical Carcinogens
OCDE
13 Aug 2007
In vivo rodent models remain the only reliable way for experimental investigation of the carcinogenic risk of chemicals to humans, however, the rodent carcinogenicity assay is expensive and time-consuming. Several in vitro alternatives to...
Detailed Review Paper on Environmental Endocrine Disruptor Screening: The Use of Estrogen and Androgen Receptor Binding and Transactivation Assays in Fish
OCDE
16 Sept 2010
The current Detailed Review Paper (DRP) has been developed under the Validation Management Groups for Ecotoxicity Testing (VMGeco) and Non-Animal testing (VMG NA). The DRP focuses on estrogen and androgen in vitro receptor and transcriptional...
Detailed Review Paper on Fish Life-Cycle Tests
OCDE
25 Jul 2008
The principal purpose of this Detailed Review Paper (DRP) is to define the basis, objectives and conduct of fish life-cycle tests for the effects of endocrine disrupting chemicals (EDCs). The main focus is on four species of fish (fathead minnow...
Detailed Review Paper on Fish Screening Assays for the Detection of Endocrine Active Substances
OCDE
01 Nov 2004
This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of fish screening assays for chemicals active at the endocrine level on the reproductive system of test animals.
Detailed Review Paper on In Vitro Test Addressing Immunotoxicity With a Focus on Immunosuppression
OCDE
19 Sept 2022
This Detailed Review Paper (DRP) aims to present and discuss the application and interpretation of in vitro immunotoxicity assays, mainly covering immunosuppression, and to define an in vitro tiered approach to testing and assessment. A...
Detailed Review Paper on Thyroid Hormone Disruption Assays
OCDE
02 Aug 2006
This document reviews the state of assays for thyroid toxicants across four vertebrate classes (fish, amphibians, birds and mammals) within the context of a thorough review of thyroid endocrinology across these taxa. Considering the similarity of the...
Detailed Review Paper on Transgenic Rodent Mutation Assays
OCDE
23 Jul 2009
Induced chromosomal and gene mutations cause genetic diseases, birth defects and other disease conditions and play a role in carcinogenesis. While it is widely accepted that in vivo mutation assays are more relevant to the human condition than in...
This paper provides methods for both the mechanistic evaluation of the action of Endocrine Disrupter Chemicals (EDCs).
Detailed Review Paper on the Use of Metabolising Systems for In Vitro Testing of Endocrine Disruptors
OCDE
03 Sept 2014
This Detailed Review Paper describes some endocrine pathways that have been shown to be susceptible to environmental endocrine disruption and whose disruption could contribute to increasing incidents of some disorders in humans and wildlife populations.
Detailed Review Paper on the miniaturised versions of the bacterial reverse gene mutation test
OCDE
19 Sept 2022
The bacterial reverse gene mutation test described in OECD Test Guideline 471 is the most widely used in vitro test for the detection of mutagenicity. The standard format utilises plate incorporation and/or preincubation method; a test mixture...
International standardised test guidelines (TGs) with sensitive endpoints form the basis for hazard identification and characterisation and risk assessment used in the regulation of chemicals. The OECD has developed the Conceptual Framework for the...
Detailed review paper on the Retinoid System
OCDE
21 Sept 2021
The aim of this document is to provide a more detailed overview of the understanding of the role of retinoid signalling in several organ systems for which more information may be known, as well as evaluate potential gaps in knowledge, and identify...